LRRC10 - leucine rich repeat containing 10 Gene

Homo sapiens

Also known as HRLRRP; LRRC10A

Gene ID: 376132 | Gene type: protein coding

About LRRC10

Cytogenetic location: 12q15 Genomic coordinates (GRCh38): 12:69,608,564-69,610,907 (from NCBI)

This gene has 1 transcript (splice variant), 110 orthologues and 31 paralogues.

Summary

Predicted to enable actin binding activity. Predicted to be involved in cardiac muscle cell development. Predicted to be located in myofibril. Predicted to be active in Cytoskeleton and sarcomere. [provided by Alliance of Genome Resources, Apr 2022]

LRRC10 Products(1)

mRNA	Protein	Name
NM_201550.4	NP_963844.2	leucine-rich repeat-containing protein 10

LRRC10 Protein Structure

LRR_4

LRR_1

0
100
200
277 a.a.

Protein Preferred Names

Protein Names

leucine-rich repeat-containing protein 10

heart-restricted leucine-rich repeat protein

Related Diseases

Diseases

Alias

Intellectual Developmental Disorder With Cardiac Arrhythmia

Gnb5-Related Intellectual Disability-Cardiac Arrhythmia Syndrome	IDDCA
Intellectual Developmental Disorder, With Cardiac Arrhythmia

Anomalous Left Coronary Artery From The Pulmonary Artery

Bland White Garland Syndrome	Alcapa
Bland-White-Garland Syndrome	White-Garland Syndrome

Brugada Syndrome

Sudden Unexpected Nocturnal Death Syndrome	Sudden Unexplained Nocturnal Death Syndrome
Bangungut	Brugada Type Idiopathic Ventricular Fibrillation
Pokkuri Death Syndrome	Sunds
Idiopathic Ventricular Fibrillation, Brugada Type	Sudden Unexplained Death
Dream Disease	Right Bundle Branch Block, St Segment Elevation, And Sudden Death Syndrome
Sudden Unexplained Death Syndrome	Suds
Sunds - [Sudden Unexplained Nocturnal Death Syndrome]

Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy	Primary Dilated Cardiomyopathy
Idiopathic Dilated Cardiomyopathy	Congestive Cardiomyopathy
Idiopathic Dilation Cardiomyopathy	Primary Familial Dilated Cardiomyopathy
Cardiomyopathy, Dilated	DCM
Cardiomyopathy, Familial Dilated	Dilated Cardiomyopathy, Familial
Hypokinetic Dilated Cardiomyopathy, Familial	Familial Idiopathic Cardiomyopathy
Fdc	Cardiomyopathy, Familial Idiopathic
Idiopathic Cardiomegaly	Dilated Congestive Cardiomyopathy
Chronic Dilated Cardiomyopathy	Ccm - [Congestive Cardiomyopathy]
Cocm - [Congestive Cardiomyopathy]	Dcm - [Dilated Cardiomyopathy]
Dilated-Hypokinetic Cardiomyopathy	Congestive Idiopathic Cardiomyopathy
Primary Idiopathic Dilated Cardiomyopathy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07807	LRRC10 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	LRRC10	VGNC	VGNC:52796
Rattus norvegicus	LRRC10	RGD	RGD:1307358
Mus musculus	LRRC10	MGD	MGI:2448063
Canis familiaris	LRRC10	VGNC	VGNC:54525
Felis catus	LRRC10	VGNC	VGNC:63286

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