2. Gene
  3. Rph3al - rabphilin 3A-like (without C2 domains) Gene

Rph3al - rabphilin 3A-like (without C2 domains) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Noc2; Gm1753

Gene ID: 380714 | Gene type: protein coding

About Rph3al

Summary

Predicted to enable LIM domain binding activity. Involved in glucose homeostasis and positive regulation of Insulin secretion. Acts upstream of or within negative regulation of G protein-coupled receptor signaling pathway and regulation of calcium ion-dependent exocytosis. Predicted to be located in secretory granule membrane. Orthologous to human RPH3AL (rabphilin 3A like (without C2 domains)). [provided by Alliance of Genome Resources, Apr 2022]

Rph3al Products(2)

mRNA Protein Name
NM_001291159.1 NP_001278088.1 rab effector Noc2 isoform 2
NM_029548.4 NP_083824.1 rab effector Noc2 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11598194 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
15159548 MGI
involved in glucose homeostasis IDA
IDA: Inferred from direct assay
11598194 MGI
acts upstream of or within glucose homeostasis IMP
IMP: Inferred from mutant phenotype
15159548 MGI
acts upstream of or within negative regulation of G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
15159548 MGI
involved in positive regulation of insulin secretion IDA
IDA: Inferred from direct assay
15159548 MGI
acts upstream of or within regulation of calcium ion-dependent exocytosis IMP
IMP: Inferred from mutant phenotype
15159548 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rab effector Noc2

no C2 domains protein

rabphilin-3A-like protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12158 RPH3AL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rph3al NCBI NCBI:9501