Ighd - immunoglobulin heavy constant delta Gene

Also Known as IgD; Igh-5

Species: Mus musculus

Gene Type: other
Gene ID: 380797

Summary

Enables antigen binding activity. Acts upstream of or within several processes, including immunoglobulin mediated immune response; positive regulation of B cell proliferation; and somatic hypermutation of immunoglobulin genes. Located in external side of plasma membrane. Part of B cell receptor complex. Orthologous to human IGHD (immunoglobulin heavy constant delta). [provided by Alliance of Genome Resources, Apr 2022]

Molecular Function GO Annotation Evidence References Source
enables antigen binding IMP
IMP: Inferred from mutant phenotype
8418208 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of B cell proliferation IDA
IDA: Inferred from direct assay
8666928 MGI
acts upstream of or within immunoglobulin mediated immune response IMP
IMP: Inferred from mutant phenotype
8418208 MGI
acts upstream of or within positive regulation of B cell proliferation IDA
IDA: Inferred from direct assay
8666928 MGI
acts upstream of or within regulation of immune response IMP
IMP: Inferred from mutant phenotype
8418208 MGI
acts upstream of or within somatic hypermutation of immunoglobulin genes IMP
IMP: Inferred from mutant phenotype
8418208 MGI
Cellular Component GO Annotation Evidence References Source
part of B cell receptor complex IDA
IDA: Inferred from direct assay
8418208 MGI
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
8041705 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Orthologs Information

Species Symbol Source ID
Homo sapiens Ighd NCBI NCBI:3495