2. Gene
  3. Pdp1 - pyruvate dehydrogenase phosphatase catalytic subunit 1 Gene

Pdp1 - pyruvate dehydrogenase phosphatase catalytic subunit 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ppm2c; Gm1024

Gene ID: 381511 | Gene type: protein coding

About Pdp1

Summary

Predicted to enable metal ion binding activity and phosphoprotein Phosphatase activity. Predicted to be involved in peptidyl-threonine dephosphorylation and positive regulation of pyruvate dehydrogenase activity. Located in mitochondrion. Human ortholog(s) of this gene implicated in obesity and pyruvate decarboxylase deficiency. Orthologous to human PDP1 (pyruvate dehydrogenase Phosphatase catalytic subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Pdp1 Products(5)

mRNA Protein Name
NM_001033453.3 NP_001028625.1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial isoform c
NM_001098230.1 NP_001091700.1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial isoform b
NM_001098231.1 NP_001091701.1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial isoform a
NM_001290387.1 NP_001277316.1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial isoform d
NM_001290391.1 NP_001277320.1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial isoform b
Protein Preferred Names Protein Names

[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

PDP 1

PDPC 1

protein phosphatase 2C, magnesium dependent, catalytic subunit

pyruvate dehydrogenase phosphatase isoenzyme 2

pyruvate dehyrogenase phosphatase catalytic subunit 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10285 PDP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdp1 NCBI NCBI:54704