FENDRR - FOXF1 adjacent non-coding developmental regulatory RNA Gene

Also Known as FOXF1AS1; FOXF1-AS1; lincFOXF1; TCONS_00024240; onco-lncRNA-21

Species: Homo sapiens

Gene Type: ncRNA
Gene ID: 400550

About FENDRR

Cytogenetic location: 16q24.1 Genomic coordinates (GRCh38): 16:86,474,525-86,508,860 (from NCBI)

This gene has 14 transcripts (splice variants). Biased expression in lung (RPKM 13.0), urinary bladder (RPKM 9.3) and 9 other tissues.

Summary

This gene produces a spliced long non-coding RNA transcribed bidirectionally with FOXF1 on the opposite strand. A similar gene in mouse is essential for normal development of the heart and body wall. The encoded transcript is thought to act by binding to polycomb repressive complex 2 (PRC2) and/or TrxG/MLL complexes to promote the methylation of the promoters of target genes, thus reducing their expression. It has been suggested that this transcript may play a role in the progression of gastric Cancer. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]

Related Diseases

Diseases Alias
Alveolar Capillary Dysplasia With Misalignment Of Pulmonary Veins

  • Alveolar Capillary Dysplasia

  • ACDMPV

  • Alveolar Capillary Dysplasia With Pulmonary Venous Misalignment

  • Congenital Alveolar Capillary Dysplasia

  • Alveolar Capillary Dysplasia With Misalignment Of Pulmonary Veins And Other Congenital Anomalies

  • Familial Persistent Pulmonary Hypertension Of The Newborn

  • Acd

  • Pulmonary Hypertension, Familial Persistent Of The Newborn

  • Acd/Mpv

  • Misalignment Of The Pulmonary Vessels

  • Alveolar Capillary Dysplasia With Misalignment Of Pulmonary Vessels

  • Dysplasia, Capillary, Alveolar, With Misalignment Of Pulmonary Veins

  • Persistent Fetal Circulation Syndrome
Pulmonary Disease, Chronic Obstructive

  • Chronic Obstructive Pulmonary Disease

  • COPD

  • Pulmonary Disease, Chronic Obstructive, Severe Early-Onset

  • Chronic Obstructive Lung Disease

  • Chronic Obstructive Airway Disease

  • Pulmonary Disease, Chronic Obstructive, Susceptibility To

  • Cold

  • Severe Early-Onset Chronic Obstructive Pulmonary Disease

  • Pulmonary Disease Chronic Obstructive

  • Pulmonary Disease, Obstructive, Chronic, Susceptibility To

  • Chronic Obstructive Pulmonary Disease Of Horses

  • Common Cold

  • Upper Respiratory Infections

  • Copd - [Chronic Obstructive Pulmonary Disease]

  • Coad - [Chronic Obstructive Airways Disease]

  • Cold - [Chronic Obstructive Lung Disease]

  • Chronic Airway Disease Nos

  • Chronic Airways Limitation, Unspecified

  • Chronic Obstructed Airway, Unspecified

  • Chronic Obstructive Airway Disease, Unspecified

  • Chronic Obstructive Airway, Unspecified

  • Obstructive Lung Disease Nos

  • Chronic Obstructive Lung Disease Nos

  • Chronic Obstructive Lung Nos

  • Obstructive Pulmonary Disease Nos

  • Exacerbation Copd Nos

  • Acute Exacerbation Copd
Lung Cancer Susceptibility 3

  • Lung Adenocarcinoma

  • Adenocarcinoma Of Lung

  • LNCR3

  • Adenocarcinoma Of Lung, Susceptibility To

  • Bronchogenic Lung Adenocarcinoma

  • Nonsmall Cell Adenocarcinoma

  • Adenocarcinoma Lung

  • Lung Adenocarcinomas

  • Non-Small Cell Adenocarcinoma
Gallbladder Cancer

  • Gallbladder Carcinoma

  • Gallbladder Neoplasm

  • Malignant Neoplasm Of Gallbladder

  • Malignant Tumour Of Gallbladder

  • Gallbladder Ca

  • Localized Malignant Gallbladder Neoplasm

  • Malignant Tumor Of The Gallbladder

  • Tumor Of The Gallbladder

  • Cancer Of The Gallbladder

  • Carcinoma Gallbladder

  • Carcinoma Of Gallbladder

  • Gallbladder Neoplasms

  • Malignant Neoplasm Of Gallbladder Localized

  • Cancer Of Gallbladder

  • Primary Malignant Neoplasm Of Gallbladder
Gastric Cancer

  • Stomach Cancer

  • Gastric Carcinoma

  • Stomach Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach
Osteogenic Sarcoma

  • Osteosarcoma

  • OSRC

  • Osteosarcoma, Somatic

  • Neoplasms, Bone Tissue

  • Bone Tissue Neoplasm

  • Osteoid Sarcoma

  • Skeletal Sarcoma

  • Osteosarcoma Of Bone

  • Bone Sarcoma
Prostate Cancer

  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer
Lung Cancer

  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Susceptibility To

  • Lung Cancer, Protection Against

  • Adenocarcinoma Of Lung, Somatic

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma
Omphalocele

  • Omphalocoele

  • Congenital Omphalocele

  • Exomphalos

  • Exumbilication
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus FENDRR MGD MGI:1916040
Rattus norvegicus FENDRR RGD RGD:9685086