2. Gene
  3. Gnptab - N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits Gene

Gnptab - N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as EG432486

Gene ID: 432486 | Gene type: protein coding

About Gnptab

Summary

Predicted to enable UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity. Acts upstream of or within carbohydrate phosphorylation and secretion of lysosomal Enzymes. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Used to study mucolipidosis II alpha/beta. Human ortholog(s) of this gene implicated in mucolipidosis II alpha/beta and mucolipidosis III alpha/beta. Orthologous to human GNPTAB (N-acetylglucosamine-1-phosphate transferase subunits alpha and beta). [provided by Alliance of Genome Resources, Apr 2022]

Gnptab Products(2)

mRNA Protein Name
NM_001004164.3 NP_001004164.2 N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform 1
NM_001364707.1 NP_001351636.1 N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within carbohydrate phosphorylation IMP
IMP: Inferred from mutant phenotype
17652091 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
17652091 MGI
acts upstream of or within protein secretion IMP
IMP: Inferred from mutant phenotype
17652091 MGI
acts upstream of or within secretion of lysosomal enzymes IMP
IMP: Inferred from mutant phenotype
19710420 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N-acetylglucosamine-1-phosphotransferase subunits alpha/beta

UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta

glcNAc-1-phosphotransferase subunits alpha/beta

stealth protein GNPTAB

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-E70305 GlcNAc-1-Phosphotransferase / Unkown
HY-RS05574 GNPTAB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gnptab NCBI NCBI:79158