2. Gene
  3. Dnaaf5 - dynein, axonemal assembly factor 5 Gene

Dnaaf5 - dynein, axonemal assembly factor 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Heatr2

Gene ID: 433956 | Gene type: protein coding

About Dnaaf5

Summary

Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in cilium movement; inner dynein arm assembly; and outer dynein arm assembly. Predicted to act upstream of or within cell projection organization. Located in cytoplasm. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 18. Orthologous to human DNAAF5 (dynein axonemal assembly factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Dnaaf5 Products(2)

mRNA Protein Name
NM_001081265.2 NP_001074734.1 dynein axonemal assembly factor 5 isoform 1
NM_001363485.1 NP_001350414.1 dynein axonemal assembly factor 5 isoform 2
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
25232951 MGI
NOT located in motile cilium IDA
IDA: Inferred from direct assay
25232951 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dynein axonemal assembly factor 5

HEAT repeat-containing protein 2

dynein assembly factor 5, axonemal

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03841 DNAAF5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dnaaf5 NCBI NCBI:54919