2. Gene
  3. Kcnk18 - potassium two pore domain channel subfamily K member 18 Gene

Kcnk18 - potassium two pore domain channel subfamily K member 18 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Tresk-2

Gene ID: 445371 | Gene type: protein coding

About Kcnk18

Summary

Predicted to enable calcium-activated Potassium Channel activity; outward rectifier Potassium Channel activity; and potassium ion leak channel activity. Predicted to be involved in cellular response to pH; potassium ion export across plasma membrane; and stabilization of membrane potential. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in migraine with aura. Orthologous to human KCNK18 (potassium two pore domain channel subfamily K member 18). [provided by Alliance of Genome Resources, Apr 2022]

Kcnk18 Products(2)

mRNA Protein Name
NM_001003820.2 NP_001003820.1 potassium channel subfamily K member 18 isoform 1
NM_001134912.2 NP_001128384.1 potassium channel subfamily K member 18 isoform 2
Protein Preferred Names Protein Names

potassium channel subfamily K member 18

potassium channel, subfamily K, member 18

potassium channel, two pore domain subfamily K, member 18

tandem-pore K+ (K(2P)) channel

two-pore-domain potassium channel TRESK

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07157 KCNK18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnk18 NCBI NCBI:338567