Fbxl7 - F-box and leucine-rich repeat protein 7 Gene

Mus musculus

Also known as FBL7; Fbl6; D230018M15Rik

Gene ID: 448987 | Gene type: protein coding

About Fbxl7

Summary

Involved in G2/M transition of mitotic cell cycle; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; and protein polyubiquitination. Located in centrosome. Part of SCF ubiquitin Ligase complex. Orthologous to human FBXL7 (F-box and leucine rich repeat protein 7). [provided by Alliance of Genome Resources, Apr 2022]

Fbxl7 Products(1)

mRNA	Protein	Name
NM_176959.3	NP_795933.2	F-box/LRR-repeat protein 7

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	22306998	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in G2/M transition of mitotic cell cycle	IDA IDA: Inferred from direct assay	22306998	MGI
involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IMP IMP: Inferred from mutant phenotype	22306998	MGI
involved in mitotic cell cycle	IMP IMP: Inferred from mutant phenotype	22306998	MGI
involved in protein polyubiquitination	IMP IMP: Inferred from mutant phenotype	25778398	MGI
involved in protein ubiquitination	IDA IDA: Inferred from direct assay	22306998	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of SCF ubiquitin ligase complex	IDA IDA: Inferred from direct assay	22306998	MGI
located in centrosome	IDA IDA: Inferred from direct assay	22306998	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

F-box/LRR-repeat protein 7

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04794	FBXL7 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-111899	7-Ethoxyrosmanol		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Fbxl7	NCBI	NCBI:23194

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