Fbxl7 - F-box and leucine-rich repeat protein 7 Gene

Also Known as FBL7; Fbl6; D230018M15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 448987

Summary

Involved in G2/M transition of mitotic cell cycle; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; and protein polyubiquitination. Located in centrosome. Part of SCF ubiquitin Ligase complex. Orthologous to human FBXL7 (F-box and leucine rich repeat protein 7). [provided by Alliance of Genome Resources, Apr 2022]

Fbxl7 Products (1)

mRNA Protein Name
NM_176959.3 NP_795933.2 F-box/LRR-repeat protein 7

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22306998 MGI
Biological Process GO Annotation Evidence References Source
involved in G2/M transition of mitotic cell cycle IDA
IDA: Inferred from direct assay
22306998 MGI
involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
22306998 MGI
involved in mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
22306998 MGI
involved in protein polyubiquitination IMP
IMP: Inferred from mutant phenotype
25778398 MGI
involved in protein ubiquitination IDA
IDA: Inferred from direct assay
22306998 MGI
Cellular Component GO Annotation Evidence References Source
part of SCF ubiquitin ligase complex IDA
IDA: Inferred from direct assay
22306998 MGI
located in centrosome IDA
IDA: Inferred from direct assay
22306998 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-box/LRR-repeat protein 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04794 FBXL7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-111899 7-Ethoxyrosmanol / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fbxl7 NCBI NCBI:23194