S1PR2 - sphingosine-1-phosphate receptor 2 Gene

Also Known as EDG5

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 484959

About S1PR2

Primary_assembly 20: 51,376,966-51,384,411 forward strand.ROS_Cfam_1.0:CM025119.1

This gene has 2 transcripts (splice variants), 192 orthologues and 16 paralogues.

S1PR2 Products (2)

mRNA Protein Name
XM_038428670.1 XP_038284598.1 sphingosine 1-phosphate receptor 2
XM_038428671.1 XP_038284599.1 sphingosine 1-phosphate receptor 2

S1PR2 Protein Structure

7tmA_S1PR2_Edg5

7tmA_S1PR2_Edg5: cd15347 (33 - 298)

7tmA_S1PR2_Edg5

7tmA_S1PR2_Edg5: cd15347 (34 - 60)

7tmA_S1PR2_Edg5

7tmA_S1PR2_Edg5: cd15347 (67 - 92)

7tmA_S1PR2_Edg5

7tmA_S1PR2_Edg5: cd15347 (104 - 134)

7tmA_S1PR2_Edg5

7tmA_S1PR2_Edg5: cd15347 (145 - 165)

7tmA_S1PR2_Edg5

7tmA_S1PR2_Edg5: cd15347 (185 - 214)

7tmA_S1PR2_Edg5

7tmA_S1PR2_Edg5: cd15347 (225 - 255)

7tmA_S1PR2_Edg5

7tmA_S1PR2_Edg5: cd15347 (266 - 291)

  • 0
  • 100
  • 200
  • 300
  • 352 a.a.
Protein Preferred Names Protein Names

sphingosine 1-phosphate receptor 2

  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 5

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12355 Siponimod Agonist 99.95% Yes
HY-12355A Siponimod hemifumarate Agonist 99.64% Yes

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-111253 CYM-5478 Agonist 99.90% Unkown
HY-139310 GLPG2938 Antagonist 99.94% Unkown
HY-176533 S1PR5-IN-1 Inhibitor 99.58% Unkown
HY-N1423B Glycocholic acid hydrate Activator 99.85% Unkown
HY-113934 L-threo Lysosphingomyelin (d18:1) Agonist 98.0% Unkown
HY-120409 AB1 Inhibitor / Unkown
HY-182618 XAX-162 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens S1PR2 NCBI NCBI:9294
Mus musculus S1PR2 NCBI NCBI:14739