TIGIT - T cell immunoreceptor with Ig and ITIM domains Gene

Canis lupus familiaris (sub-species: familiaris)

Also known as VSIG9; VSTM3

Gene ID: 487986 | Gene type: protein coding

About TIGIT

mRNA	Protein	Name
XM_038444991.1	XP_038300919.1	T-cell immunoreceptor with Ig and ITIM domains isoform X2
XM_038444990.1	XP_038300918.1	T-cell immunoreceptor with Ig and ITIM domains isoform X1

Protein Preferred Names

Protein Names

T-cell immunoreceptor with Ig and ITIM domains

V-set and immunoglobulin domain containing 9

V-set and transmembrane domain containing 3

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-A0070A	Liothyronine	Activator	99.82%	Unkown

Clinical Phase

Inhibitory Antibodies (8)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P9986	Tiragolumab	Inhibitor	99.04%	Phase 3
HY-P99858	Domvanalimab	Inhibitor	98.62%	Phase 3
HY-P990032	Belrestotug	Inhibitor	97%	Phase 3
HY-P990704	Rilvegostomig		99.00%	Phase 3
HY-P99202	Vibostolimab	Inhibitor	96.54%	Phase 2
HY-P990079	Renvistobart	Inhibitor	99.95%	Phase 2
HY-P990031	Dargistotug		99.36%	Phase 2
HY-P990030	Ralzapastotug	Inhibitor	98.67%	Phase 1

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-185098	PD1-PDL1-IN-4	Inhibitor	/	Unkown
HY-A0070AS5	Liothyronine-d4		/	Unkown
HY-RS14524	TIGIT Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS16565	Tigit Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22998	Tigit Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Inhibitory Antibodies (15)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990155	Anti-Mouse TIGIT Antibody (1G9)	Inhibitor	99.71%	Unkown
HY-P990960	Lucorafusp alfa		/	Unkown
HY-P990746	Lancastotug	Inhibitor	95.432%	Unkown
HY-P991389	BAT-6005	Inhibitor	95.89%	Unkown
HY-P991386	PM-1021	Inhibitor	/	Unkown
HY-P991387	AGEN1307	Inhibitor	/	Unkown
HY-P991390	BAT-6021	Inhibitor	/	Unkown
HY-P991393	ASP8374		/	Unkown
HY-P991394	SEA-TGT	Inhibitor	/	Unkown
HY-P991475	MG-1131		/	Unkown
HY-P991620	JS006	Inhibitor	/	Unkown
HY-P992121	Nilvanstomig	Inhibitor	/	Unkown
HY-P992361	HB0030		/	Unkown
HY-P991111	Anti-Mouse TIGIT Antibody (10A7)	Inhibitor	98.37%	Unkown
HY-P991391	COM902	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	TIGIT	NCBI	NCBI:201633
Macaca fascicularis	TIGIT	NCBI	NCBI:102121588
Mus musculus	TIGIT	NCBI	NCBI:100043314
Leporidae	TIGIT	NCBI
Rattus norvegicus	TIGIT	NCBI	NCBI:363784

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