PD1-PDL1-IN-4
PD1-PDL1-IN-4 (compound 19) is a potent and orally active PD1-PDL1 inhibitor that modulates TIGIT and PD-1 signalling pathways. PD1-PDL1-IN-4 can rescue CD8+ T cell and mouse splenocyte proliferation. PD1-PDL1-IN-4 inhibits tumor growth in a CT26 syngeneic colon adenocarcinoma mouse model. PD1-PDL1-IN-4 can be used for research on colon cancer.
For research use only. We do not sell to patients.
- CAS No.: 2007110-15-6
- Formula: C19H25N5O6
- Molecular Weight:419.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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TIGIT |
Chemical Information
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CAS No. 2007110-15-6
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Molecular Weight 419.43
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Formula C19H25N5O6
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SMILES
OC(C=C1)=CC=C1C[C@@H](C2=NC([C@@H](N)[C@@H](O)C)=NO2)NC(N3[C@@H](CCC3)C(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)