2. Gene
  3. Irx5 - iroquois homeobox 5 Gene

Irx5 - iroquois homeobox 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 498918 | Gene type: protein coding

About Irx5

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including embryonic cranial skeleton morphogenesis; gonad development; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within neuron differentiation; regulation of gene expression; and regulation of heart rate. Predicted to be active in nucleus. Orthologous to human IRX5 (iroquois homeobox 5). [provided by Alliance of Genome Resources, Apr 2022]

Irx5 Products(1)

mRNA Protein Name
NM_001030044.1 NP_001025215.1 iroquois-class homeodomain protein IRX-5
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
18815185 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
18815185 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
18815185 RGD
Biological Process GO Annotation Evidence Reference Source
involved in regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18815185 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

iroquois-class homeodomain protein IRX-5

iroquois homeobox protein 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06920 IRX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06924 IRX5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Irx5 NCBI NCBI:10265