Pot1 - protection of telomeres 1 Gene

Rattus norvegicus

Also known as Pot1a

Gene ID: 500054 | Gene type: protein coding

About Pot1

Summary

Predicted to enable DEAD/H-box RNA helicase binding activity; DNA binding activity; and Telomerase Inhibitor activity. Predicted to be involved in several processes, including establishment of protein localization to telomere; regulation of DNA metabolic process; and telomere organization. Predicted to act upstream of or within chromosome organization. Predicted to be located in chromosome, telomeric region and nucleoplasm. Predicted to be part of shelterin complex. Human ortholog(s) of this gene implicated in familial melanoma and high grade glioma. Orthologous to human POT1 (protection of telomeres 1). [provided by Alliance of Genome Resources, Apr 2022]

Pot1 Products(2)

mRNA	Protein	Name
NM_001395151.1	NP_001382080.1	protection of telomeres protein 1
NM_001395152.1	NP_001382081.1	protection of telomeres protein 1

Protein Preferred Names

Protein Names

protection of telomeres protein 1

protection of telomeres 1 homolog

protection of telomeres 1A

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10885	POT1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pot1	NCBI	NCBI:25913

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