Hs6st1 - heparan sulfate 6-O-sulfotransferase 1 Gene

Also Known as 6Ost1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50785

Summary

Enables heparan sulfate 6-O-sulfotransferase activity. Acts upstream of or within blood vessel development; heparan sulfate proteoglycan biosynthetic process, enzymatic modification; and lung alveolus development. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 15 with or without anosmia. Orthologous to human HS6ST1 (heparan sulfate 6-O-sulfotransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Hs6st1 Products (1)

mRNA Protein Name
NM_015818.2 NP_056633.2 heparan-sulfate 6-O-sulfotransferase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heparan sulfate 6-O-sulfotransferase activity IDA
IDA: Inferred from direct assay
10644753 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within angiogenesis IMP
IMP: Inferred from mutant phenotype
17405882 MGI
involved in heparan sulfate proteoglycan biosynthetic process IDA
IDA: Inferred from direct assay
12611590 MGI
acts upstream of or within heparan sulfate proteoglycan biosynthetic process IMP
IMP: Inferred from mutant phenotype
17405882 MGI
involved in heparan sulfate proteoglycan biosynthetic process IMP
IMP: Inferred from mutant phenotype
30377379 MGI
acts upstream of or within heparan sulfate proteoglycan biosynthetic process, enzymatic modification IDA
IDA: Inferred from direct assay
10644753 MGI
acts upstream of or within labyrinthine layer blood vessel development IMP
IMP: Inferred from mutant phenotype
17405882 MGI
acts upstream of or within lung alveolus development IMP
IMP: Inferred from mutant phenotype
17405882 MGI
Cellular Component GO Annotation Evidence References Source
is active in Golgi apparatus IDA
IDA: Inferred from direct assay
15226404 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heparan-sulfate 6-O-sulfotransferase 1

  • HS6ST-1

  • mHS6ST-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06382 HS6ST1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hs6st1 NCBI NCBI:9394