LGSN - lengsin, lens protein with glutamine synthetase domain Gene
Also Known as LGS; GLULD1
Species: Homo sapiens
About LGSN
This gene has 4 transcripts (splice variants), 201 orthologues and 1 paralogue. Low expression observed in reference dataset.
Summary
This gene encodes a protein with similarity to the GS I members of the glutamine synthetase superfamily. The encoded protein is referred to as a pseudo-glutamine synthetase because it has no glutamine synthesis activity and may function as a chaperone protein. This protein is localized to the lens and may be associated with cataract disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
LGSN Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001143940.2 | NP_001137412.1 | lengsin isoform b |
| NM_016571.3 | NP_057655.2 | lengsin isoform a |
LGSN Protein Structure
Gln-synt_N: Glutamine synthetase, beta-Grasp domain (87 - 174)
Gln-synt_C: Glutamine synthetase, catalytic domain (182 - 427)
- 0
- 100
- 200
- 300
- 400
- 509 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
lengsin |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Mature Cataract |
|
|
| Presbyopia |
|
|
| Cataract |
|
|
| Retinitis Pigmentosa |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS07621 | LGSN Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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