2. Gene
  3. ST7L - suppression of tumorigenicity 7 like Gene

ST7L - suppression of tumorigenicity 7 like Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as ST7R; STLR; FAM4B

Gene ID: 54879 | Gene type: protein coding

About ST7L

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:112,517,803-112,619,684 (from NCBI)

This gene has 28 transcripts (splice variants), 210 orthologues and 1 paralogue. Broad expression in testis (RPKM 6.6), skin (RPKM 3.2) and 24 other tissues.

Summary

This gene was identified by its similarity to the ST7 tumor suppressor gene found in the chromosome 7q31 region. This gene is clustered in a tail-to-tail manner with the WNT2B gene in a chromosomal region known to be deleted and rearranged in a variety of cancers. Several transcript variants encoding many different isoforms have been described, but some have not been fully characterized. [provided by RefSeq, Feb 2011]

ST7L Products(5)

mRNA Protein Name
NM_001308264.2 NP_001295193.1 suppressor of tumorigenicity 7 protein-like isoform 7
NM_017744.5 NP_060214.2 suppressor of tumorigenicity 7 protein-like isoform 1
NM_138727.4 NP_620055.1 suppressor of tumorigenicity 7 protein-like isoform 2
NM_138728.3 NP_620056.1 suppressor of tumorigenicity 7 protein-like isoform 3
NM_138729.4 NP_620057.1 suppressor of tumorigenicity 7 protein-like isoform 4

ST7L Protein Structure

ST7

ST7: ST7 protein (43 - 549)

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  • 575 a.a.
Protein Preferred Names Protein Names

suppressor of tumorigenicity 7 protein-like

ST7-related protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13855 ST7L Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ST7L RGD RGD:1359336
Bos taurus ST7L VGNC VGNC:35343
Macaca mulatta ST7L VGNC VGNC:77954
Felis catus ST7L VGNC VGNC:65735
Canis familiaris ST7L VGNC VGNC:46863
Mus musculus ST7L MGD MGI:2386964