2. Gene
  3. CELF4 - CUGBP Elav-like family member 4 Gene

CELF4 - CUGBP Elav-like family member 4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CELF-4; BRUNOL4

Gene ID: 56853 | Gene type: protein coding

About CELF4

Cytogenetic location: 18q12.2 Genomic coordinates (GRCh38): 18:37,242,844-37,565,798 (from NCBI)

This gene has 23 transcripts (splice variants), 220 orthologues and 6 paralogues. Biased expression in brain (RPKM 27.2) and adrenal (RPKM 3.4).

Summary

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

CELF4 Products(71)

mRNA Protein Name
NM_001025087.2 NP_001020258.1 CUGBP Elav-like family member 4 isoform 2
NM_001025088.2 NP_001020259.1 CUGBP Elav-like family member 4 isoform 3
NM_001025089.2 NP_001020260.1 CUGBP Elav-like family member 4 isoform 4
NM_001330603.2 NP_001317532.1 CUGBP Elav-like family member 4 isoform 5
NM_001353695.2 NP_001340624.1 CUGBP Elav-like family member 4 isoform 35
NM_001353696.2 NP_001340625.1 CUGBP Elav-like family member 4 isoform 45
NM_001353697.2 NP_001340626.1 CUGBP Elav-like family member 4 isoform 55
NM_001353698.2 NP_001340627.1 CUGBP Elav-like family member 4 isoform 23
NM_001353699.2 NP_001340628.1 CUGBP Elav-like family member 4 isoform 59
NM_001353700.2 NP_001340629.1 CUGBP Elav-like family member 4 isoform 56
NM_001353701.2 NP_001340630.1 CUGBP Elav-like family member 4 isoform 71
NM_001353702.2 NP_001340631.1 CUGBP Elav-like family member 4 isoform 29
NM_001353703.2 NP_001340632.1 CUGBP Elav-like family member 4 isoform 13
NM_001353705.2 NP_001340634.1 CUGBP Elav-like family member 4 isoform 22
NM_001353706.2 NP_001340635.1 CUGBP Elav-like family member 4 isoform 60
NM_001353707.2 NP_001340636.1 CUGBP Elav-like family member 4 isoform 21
NM_001353708.2 NP_001340637.1 CUGBP Elav-like family member 4 isoform 44
NM_001353709.2 NP_001340638.1 CUGBP Elav-like family member 4 isoform 32
NM_001353710.2 NP_001340639.1 CUGBP Elav-like family member 4 isoform 36
NM_001353711.2 NP_001340640.1 CUGBP Elav-like family member 4 isoform 41
NM_001353712.2 NP_001340641.1 CUGBP Elav-like family member 4 isoform 31
NM_001353713.2 NP_001340642.1 CUGBP Elav-like family member 4 isoform 57
NM_001353714.2 NP_001340643.1 CUGBP Elav-like family member 4 isoform 42
NM_001353715.2 NP_001340644.1 CUGBP Elav-like family member 4 isoform 19
NM_001353716.2 NP_001340645.1 CUGBP Elav-like family member 4 isoform 53
NM_001353717.2 NP_001340646.1 CUGBP Elav-like family member 4 isoform 20
NM_001353718.2 NP_001340647.1 CUGBP Elav-like family member 4 isoform 30
NM_001353719.2 NP_001340648.1 CUGBP Elav-like family member 4 isoform 58
NM_001353720.2 NP_001340649.1 CUGBP Elav-like family member 4 isoform 61
NM_001353721.2 NP_001340650.1 CUGBP Elav-like family member 4 isoform 37
NM_001353722.2 NP_001340651.1 CUGBP Elav-like family member 4 isoform 64
NM_001353723.2 NP_001340652.1 CUGBP Elav-like family member 4 isoform 46
NM_001353724.2 NP_001340653.1 CUGBP Elav-like family member 4 isoform 26
NM_001353725.2 NP_001340654.1 CUGBP Elav-like family member 4 isoform 43
NM_001353726.2 NP_001340655.1 CUGBP Elav-like family member 4 isoform 14
NM_001353727.2 NP_001340656.1 CUGBP Elav-like family member 4 isoform 62
NM_001353728.2 NP_001340657.1 CUGBP Elav-like family member 4 isoform 16
NM_001353729.2 NP_001340658.1 CUGBP Elav-like family member 4 isoform 48
NM_001353730.2 NP_001340659.1 CUGBP Elav-like family member 4 isoform 49
NM_001353731.2 NP_001340660.1 CUGBP Elav-like family member 4 isoform 9
NM_001353732.2 NP_001340661.1 CUGBP Elav-like family member 4 isoform 63
NM_001353733.2 NP_001340662.1 CUGBP Elav-like family member 4 isoform 12
NM_001353734.2 NP_001340663.1 CUGBP Elav-like family member 4 isoform 8
NM_001353735.2 NP_001340664.1 CUGBP Elav-like family member 4 isoform 11
NM_001353736.2 NP_001340665.1 CUGBP Elav-like family member 4 isoform 50
NM_001353737.2 NP_001340666.1 CUGBP Elav-like family member 4 isoform 54
NM_001353738.2 NP_001340667.1 CUGBP Elav-like family member 4 isoform 27
NM_001353739.2 NP_001340668.1 CUGBP Elav-like family member 4 isoform 17
NM_001353740.2 NP_001340669.1 CUGBP Elav-like family member 4 isoform 6
NM_001353741.2 NP_001340670.1 CUGBP Elav-like family member 4 isoform 15
NM_001353742.2 NP_001340671.1 CUGBP Elav-like family member 4 isoform 18
NM_001353743.2 NP_001340672.1 CUGBP Elav-like family member 4 isoform 47
NM_001353744.2 NP_001340673.1 CUGBP Elav-like family member 4 isoform 24
NM_001353745.2 NP_001340674.1 CUGBP Elav-like family member 4 isoform 28
NM_001353746.2 NP_001340675.1 CUGBP Elav-like family member 4 isoform 10
NM_001353747.2 NP_001340676.1 CUGBP Elav-like family member 4 isoform 51
NM_001353748.2 NP_001340677.1 CUGBP Elav-like family member 4 isoform 33
NM_001353749.2 NP_001340678.1 CUGBP Elav-like family member 4 isoform 7
NM_001353750.2 NP_001340679.1 CUGBP Elav-like family member 4 isoform 38
NM_001353751.2 NP_001340680.1 CUGBP Elav-like family member 4 isoform 25
NM_001353752.2 NP_001340681.1 CUGBP Elav-like family member 4 isoform 34
NM_001353753.2 NP_001340682.1 CUGBP Elav-like family member 4 isoform 39
NM_001353754.2 NP_001340683.1 CUGBP Elav-like family member 4 isoform 52
NM_001353755.2 NP_001340684.1 CUGBP Elav-like family member 4 isoform 40
NM_001353756.2 NP_001340685.1 CUGBP Elav-like family member 4 isoform 65
NM_001353757.2 NP_001340686.1 CUGBP Elav-like family member 4 isoform 69
NM_001353758.2 NP_001340687.1 CUGBP Elav-like family member 4 isoform 70
NM_001353759.2 NP_001340688.1 CUGBP Elav-like family member 4 isoform 67
NM_001353760.2 NP_001340689.1 CUGBP Elav-like family member 4 isoform 68
NM_001353761.2 NP_001340690.1 CUGBP Elav-like family member 4 isoform 66
NM_020180.4 NP_064565.1 CUGBP Elav-like family member 4 isoform 1

CELF4 Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (56 - 123)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (154 - 216)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (442 - 472)

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  • 486 a.a.
Protein Preferred Names Protein Names

CUGBP Elav-like family member 4

CUG-BP- and ETR-3-like factor 4

Related Diseases

Diseases Alias
Speech And Communication Disorders

Language Disorder

Communication Disorder

Language Disorders

Communication Disorders

Speech Language Disorder

Speech-Language Disorder

Communication Impairment

Speech And Language Disorder
Specific Language Impairment

Language Impairment, Specific
Reading Disorder

Specific Reading Disorder

Reading

Dyslexia

Developmental Reading Disorder
Developmental Coordination Disorder

Motor Skills Disorders
Articulation Disorder

Phonological Disorder

Articulation Disorders

Articulation Impairment

Speech Sound Disorders
Learning Disability

Learning Disabilities

Learning Disorders

Academic Skill Disorder

Learning Disorder
Speech Disorder

Speech Disorders
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
Dyslexia
Pervasive Developmental Disorder

Pervasive Development Disorder

Pervasive Developmental Disorders

Pervasive Child Development Disorders

Autistic Behavior

Autism Spectrum Disorders
Specific Developmental Disorder
Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

ADHD

Attention Deficit Disorder

Attention Deficit-Hyperactivity Disorder, Susceptibility To

Attention Deficit Disorder With Hyperactivity

Hyperkinetic Disorder

Hyperactivity Of Childhood

Attention-Deficit/Hyperactivity Disorder

Add

Addh

Attention Deficit

Attention Deficit Disorder Of Childhood With Hyperactivity

Attention Deficit Disorder With Hyperactivity Syndrome

Hyperkinetic Syndrome

Attention-Deficit Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

Disturbance Of Activity And Attention

Disorder Of Activity And Attention

Adhd - [Attention Deficit Hyperactivity Disorder]

Hyperkinetic Disorders

Disorder Of Activity And Attention With Hyperkinesia

Attention Deficit Syndrome With Hyperactivity
Benign Epilepsy With Centrotemporal Spikes

Rolandic Epilepsy

Benign Rolandic Epilepsy

Epilepsy, Rolandic

Bcects

Benign Childhood Epilepsy With Centrotemporal Spike

Sylvan Seizures

Becrs

Bects

Bre

Benign Epilepsy Of Childhood With Centrotemporal Spikes

Benign Familial Epilepsy Of Childhood With Rolandic Spikes

Centrotemporal Epilepsy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02462 CELF4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CELF4 VGNC VGNC:70945
Bos taurus CELF4 VGNC VGNC:27169
Mus musculus CELF4 MGD MGI:1932407
Rattus norvegicus CELF4 RGD RGD:1307630
Felis catus CELF4 VGNC VGNC:107700