IGDCC4 - immunoglobulin superfamily DCC subclass member 4 Gene

Also Known as NOPE; DDM36

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57722

About IGDCC4

Cytogenetic location: 15q22.31 Genomic coordinates (GRCh38): 15:65,381,484-65,422,947 (from NCBI)

This gene has 6 transcripts (splice variants), 213 orthologues and 36 paralogues. Broad expression in ovary (RPKM 6.3), placenta (RPKM 5.2) and 17 other tissues.

Summary

Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

IGDCC4 Products (1)

mRNA Protein Name
NM_020962.3 NP_066013.1 immunoglobulin superfamily DCC subclass member 4 precursor

IGDCC4 Protein Structure

Ig_2

Ig_2: Immunoglobulin domain (49 - 89)

I-set

I-set: Immunoglobulin I-set domain (145 - 222)

I-set

I-set: Immunoglobulin I-set domain (245 - 322)

I-set

I-set: Immunoglobulin I-set domain (335 - 422)

fn3

fn3: Fibronectin type III domain (430 - 515)

fn3

fn3: Fibronectin type III domain (529 - 613)

fn3

fn3: Fibronectin type III domain (632 - 725)

fn3

fn3: Fibronectin type III domain (752 - 829)

fn3

fn3: Fibronectin type III domain (850 - 935)

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  • 1250 a.a.
Protein Preferred Names Protein Names

immunoglobulin superfamily DCC subclass member 4

  • likely ortholog of mouse neighbor of Punc E11

Related Diseases

Diseases Alias
Amelogenesis Imperfecta, Type Ia
  • Amelogenesis Imperfecta Type 1a

  • AI1A

  • Amelogenesis Imperfecta, Hypoplastic Type Ia

  • Amelogenesis Imperfecta Type Ia

  • Amelogenesis Imperfecta Hypoplastic Type Ia

  • Amelogenesis Imperfecta 1a

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus IGDCC4 VGNC VGNC:30075
Rattus norvegicus IGDCC4 RGD RGD:1310919
Felis catus IGDCC4 VGNC VGNC:80951
Canis familiaris IGDCC4 VGNC VGNC:41894
Mus musculus IGDCC4 MGD MGI:1858497
Macaca mulatta IGDCC4 VGNC VGNC:73388
Others IGDCC4 NCBI