SCML1 - Scm polycomb group protein like 1 Gene

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 6322

About SCML1

Cytogenetic location: Xp22.13 Genomic coordinates (GRCh38): X:17,737,128-17,754,985 (from NCBI)

This gene has 7 transcripts (splice variants), 152 orthologues and 18 paralogues. Broad expression in testis (RPKM 14.0), ovary (RPKM 6.6) and 24 other tissues.

Summary

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SCML1 Products (4)

mRNA	Protein	Name
NM_001037535.3	NP_001032624.1	sex comb on midleg-like protein 1 isoform c
NM_001037536.3	NP_001032625.1	sex comb on midleg-like protein 1 isoform c
NM_001037540.3	NP_001032629.1	sex comb on midleg-like protein 1 isoform a
NM_006746.6	NP_006737.2	sex comb on midleg-like protein 1 isoform b

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SCML1 Protein Structure

SAM_1

0
100
200
300
329 a.a.

Protein Preferred Names	Protein Names
sex comb on midleg-like protein 1	sex comb on midleg like 1

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09290	NHS Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS12516	SCML1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SCML1	VGNC	VGNC:76978
Rattus norvegicus	SCML1	RGD	RGD:7723901
Bos taurus	SCML1	VGNC	VGNC:56953
Others	SCML1	NCBI