GALNT11 - polypeptide N-acetylgalactosaminyltransferase 11 Gene

Also Known as GALNACT11; GALNAC-T11

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 63917

About GALNT11

Cytogenetic location: 7q36.1 Genomic coordinates (GRCh38): 7:152,025,674-152,122,340 (from NCBI)

This gene has 13 transcripts (splice variants), 205 orthologues and 19 paralogues. Broad expression in kidney (RPKM 69.9), placenta (RPKM 22.3) and 24 other tissues.

Summary

Enables Notch binding activity and polypeptide N-acetylgalactosaminyltransferase activity. Involved in protein O-linked glycosylation via threonine. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

GALNT11 Products (20)

mRNA Protein Name
NM_001304514.2 NP_001291443.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 2
NM_001371458.1 NP_001358387.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 1
NM_001371459.1 NP_001358388.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 1
NM_001371460.1 NP_001358389.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 1
NM_001371461.1 NP_001358390.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 1
NM_001371462.1 NP_001358391.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 1
NM_001371463.1 NP_001358392.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 1
NM_001371464.1 NP_001358393.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 3
NM_001371465.1 NP_001358394.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 4
NM_001371466.1 NP_001358395.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 4
NM_001371467.1 NP_001358396.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 4
NM_001371468.1 NP_001358397.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 5
NM_001371469.1 NP_001358398.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 5
NM_001371470.1 NP_001358399.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 5
NM_001371471.1 NP_001358400.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 6
NM_001371472.1 NP_001358401.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 6
NM_001371473.1 NP_001358402.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 7
NM_001371474.1 NP_001358403.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 7
NM_001371475.1 NP_001358404.1 polypeptide N-acetylgalactosaminyltransferase 11 isoform 8
NM_022087.4 NP_071370.2 polypeptide N-acetylgalactosaminyltransferase 11 isoform 1

GALNT11 Protein Structure

Glycos_transf_2

Glycos_transf_2: Glycosyl transferase family 2 (154 - 300)

Glyco_transf_7C

Glyco_transf_7C: N-terminal domain of galactosyltransferase (320 - 381)

Ricin_B_lectin

Ricin_B_lectin: Ricin-type beta-trefoil lectin domain (484 - 604)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 608 a.a.
Protein Preferred Names Protein Names

polypeptide N-acetylgalactosaminyltransferase 11

  • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11

Related Diseases

Diseases Alias
Heart Disease
  • Heart Failure

  • Congenital Heart Disease

  • Heart Diseases

  • Congenital Heart Defects

  • Congenital Heart Defect

  • Heart Malformation

  • Congenital Anomaly Of Heart

  • Heart Defect

  • Heart-Congenital Defect

  • Congenital Heart Disorder

  • Heart Defects Congenital

  • Heart Defects, Congenital

  • Heart Defects

  • Heart Disease, Congenital

  • Disease, Heart, Congenital

  • Congestive Heart Failure

Renpenning Syndrome 1
  • Renpenning Syndrome

  • Golabi-Ito-Hall Syndrome

  • Mrxs3

  • Mrxs8

  • X-Linked Intellectual Disability Due To Pqbp1 Mutations

  • RENS1

  • Sutherland-Haan X-Linked Mental Retardation Syndrome

  • Shs

  • Mrx55

  • X-Linked Intellectual Disability, Renpenning Type

  • Sutherland-Haan Syndrome

  • Mental Retardation, X-Linked, Renpenning Type

  • Mental Retardation, X-Linked, With Spastic Diplegia

  • Mental Retardation, X-Linked, Syndromic 3

  • Mental Retardation, X-Linked, Syndromic 8

  • Mental Retardation, X-Linked 55

  • Syndromic X-Linked Mental Retardation 8

  • X-Linked Mental Retardation Renpenning Type

  • X-Linked Mental Retardation With Spastic Diplegia

  • Sutherland-Haan X-Linked Intellectual Disability Syndrome

  • X-Linked Intellectual Disability With Spastic Diplegia

  • Hamel Cerebropalatocardiac Syndrome

  • Porteous Syndrome

  • X-Linked Intellectual Deficit Due To Pqbp1 Mutations

  • X-Linked Intellectual Deficit, Renpenning Type

  • X-Linked Intellectual Disability, Sutherland-Haan Type

  • Hamel Cerebro-Palato-Cardiac Syndrome

  • Renpenning Syndrome, Type 1

Adams-Oliver Syndrome
  • Adams Oliver Syndrome

  • Aos

  • Congenital Scalp Defects With Distal Limb Reduction Anomalies

  • Aplasia Cutis Congenita With Terminal Transverse Limb Defects

  • Congenital Scalp Defects With Distal Limb Anomalies

  • Limb, Scalp And Skull Defects

  • Limb Scalp And Skull Defects

  • Absence Defect Of Limbs, Scalp, And Skull

Primary Ciliary Dyskinesia
  • Immotile Cilia Syndrome

  • Kartagener Syndrome

  • Dextrocardia Bronchiectasis And Sinusitis

  • Pcd

  • Ciliary Motility Disorders

  • Ciliary Motility Disorder

  • Immotile Ciliary Syndrome

  • Ciliary Dyskinesia Primary

  • Ics

  • Polynesian Bronchiectasis

  • Dextrocardia-Bronchiectasis-Sinusitis Syndrome

  • Immotile Cilia Syndrome, Kartagener Type

  • Primary Ciliary Dyskinesia And Situs Inversus

  • Primary Ciliary Dyskinesia, Kartagener Type

  • Siewert Syndrome

  • Dyskinesia, Ciliary, Primary

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus GALNT11 MGD MGI:2444392
Macaca mulatta GALNT11 VGNC VGNC:72749
Rattus norvegicus GALNT11 RGD RGD:735097
Bos taurus GALNT11 VGNC VGNC:29224
Canis familiaris GALNT11 VGNC VGNC:41086
Felis catus GALNT11 VGNC VGNC:62443
Others GALNT11 NCBI