2. Gene
  3. SNX16 - sorting nexin 16 Gene

SNX16 - sorting nexin 16 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 64089 | Gene type: protein coding

About SNX16

Cytogenetic location: 8q21.13 Genomic coordinates (GRCh38): 8:81,799,583-81,842,185 (from NCBI)

This gene has 11 transcripts (splice variants), 237 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 6.1), esophagus (RPKM 5.5) and 24 other tissues.

Summary

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The protein encoded by this gene associates with late endosome membranes as is involved in tubule formation, Cholesterol transport, and transport of tetraspanin CD81. The encoded protein also inhibits cell migration and tumorigenesis. [provided by RefSeq, Jan 2017]

SNX16 Products(4)

mRNA Protein Name
NM_001348189.2 NP_001335118.1 sorting nexin-16 isoform c
NM_022133.4 NP_071416.2 sorting nexin-16 isoform a
NM_152836.3 NP_690049.1 sorting nexin-16 isoform a
NM_152837.3 NP_690050.1 sorting nexin-16 isoform b

SNX16 Protein Structure

PX

PX: PX domain (118 - 211)

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  • 200
  • 300
  • 344 a.a.
Protein Preferred Names Protein Names

sorting nexin-16

Related Diseases

Diseases Alias
Spinocerebellar Ataxia 15

SCA15

Spinocerebellar Ataxia Type 15

Spinocerebellar Ataxia Type 16

Sca16

Spinocerebellar Ataxia Type 15/16

Spinocerebellar Ataxia 16, Formerly

Sca16, Formerly

Spinocerebellar Ataxia 16

Sca15/16

Ataxia, Spinocerebellar, Type 15
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13529 SNX16 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SNX16 MGD MGI:1921968
Rattus norvegicus SNX16 RGD RGD:620295
Bos taurus SNX16 VGNC VGNC:35096
Canis familiaris SNX16 VGNC VGNC:46625
Macaca mulatta SNX16 VGNC VGNC:77710
Felis catus SNX16 VGNC VGNC:65546