LRTM2 - leucine rich repeats and transmembrane domains 2 Gene
Species: Homo sapiens
About LRTM2
This gene has 12 transcripts (splice variants), 1 gene allele, 274 orthologues and 25 paralogues. Restricted expression toward brain (RPKM 3.3).
Summary
Predicted to enable Roundabout binding activity and heparin binding activity. Predicted to be involved in axon guidance and negative chemotaxis. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
LRTM2 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001039029.3 | NP_001034118.1 | leucine-rich repeat and transmembrane domain-containing protein 2 precursor |
| NM_001163925.2 | NP_001157397.1 | leucine-rich repeat and transmembrane domain-containing protein 2 precursor |
| NM_001163926.2 | NP_001157398.1 | leucine-rich repeat and transmembrane domain-containing protein 2 precursor |
LRTM2 Protein Structure
LRRNT: Leucine rich repeat N-terminal domain (39 - 67)
LRR_8: Leucine rich repeat (92 - 151)
- 0
- 100
- 200
- 300
- 370 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
leucine-rich repeat and transmembrane domain-containing protein 2 |
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Related Diseases
| Diseases | Alias | |
|---|---|---|
| Spondylometaphyseal Dysplasia, Axial |
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| Preretinal Fibrosis |
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