2. Gene
  3. LRTM2 - leucine rich repeats and transmembrane domains 2 Gene

LRTM2 - leucine rich repeats and transmembrane domains 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 654429 | Gene type: protein coding

About LRTM2

This gene has 12 transcripts (splice variants), 1 gene allele, 274 orthologues and 25 paralogues. Restricted expression toward brain (RPKM 3.3).

Summary

Predicted to enable Roundabout binding activity and heparin binding activity. Predicted to be involved in axon guidance and negative chemotaxis. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

LRTM2 Products(3)

mRNA Protein Name
NM_001039029.3 NP_001034118.1 leucine-rich repeat and transmembrane domain-containing protein 2 precursor
NM_001163925.2 NP_001157397.1 leucine-rich repeat and transmembrane domain-containing protein 2 precursor
NM_001163926.2 NP_001157398.1 leucine-rich repeat and transmembrane domain-containing protein 2 precursor

LRTM2 Protein Structure

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (39 - 67)

LRR_8

LRR_8: Leucine rich repeat (92 - 151)

  • 0
  • 100
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  • 370 a.a.
Protein Preferred Names Protein Names

leucine-rich repeat and transmembrane domain-containing protein 2

Related Diseases

Diseases Alias
Spondylometaphyseal Dysplasia, Axial

Axial Spondylometaphyseal Dysplasia

SMDAX

Axial Smd

Smd Axial

Smd, Axial

Spondylometaphyseal Dysplasia Axial Type

Dysplasia, Spondylometaphyseal, Axial
Preretinal Fibrosis

Cellophane Maculopathy

Macular Puckering Of Retina

Macular Retinal Puckering

Epiretinal Membrane
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07847 LRTM2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris LRTM2 VGNC VGNC:42834
Felis catus LRTM2 VGNC VGNC:63319
Mus musculus LRTM2 MGD MGI:2141485
Bos taurus LRTM2 VGNC VGNC:31047
Rattus norvegicus LRTM2 RGD RGD:1587001