Gtf2h5 - general transcription factor IIH, polypeptide 5 Gene

Also Known as D17Wsu155e; 2700017P07Rik; 2810432H05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66467

Summary

Acts upstream of or within cellular response to gamma radiation and nucleic acid metabolic process. Predicted to be located in nucleolus. Predicted to be part of transcription factor TFIID complex; transcription factor TFIIH core complex; and transcription factor TFIIH holo complex. Is expressed in several structures, including 4-cell stage embryo; alimentary system; bone; ganglia; and telencephalon. Human ortholog(s) of this gene implicated in photosensitive trichothiodystrophy 3. Orthologous to human GTF2H5 (general transcription factor IIH subunit 5). [provided by Alliance of Genome Resources, Apr 2022]

Gtf2h5 Products (2)

mRNA Protein Name
NM_001357804.1 NP_001344733.1 general transcription factor IIH subunit 5
NM_181392.3 NP_852057.2 general transcription factor IIH subunit 5

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28888655 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to gamma radiation IMP
IMP: Inferred from mutant phenotype
23637614 MGI
acts upstream of or within maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
IMP: Inferred from mutant phenotype
23562818 MGI
acts upstream of or within nucleotide-excision repair IMP
IMP: Inferred from mutant phenotype
23637614 MGI
acts upstream of or within nucleotide-excision repair, preincision complex assembly IMP
IMP: Inferred from mutant phenotype
23637614 MGI
acts upstream of or within transcription elongation by RNA polymerase I IMP
IMP: Inferred from mutant phenotype
23562818 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

general transcription factor IIH subunit 5

  • TFB5 ortholog

  • TFIIH basal transcription factor complex TTD-A subunit

  • TFIIH subunit p8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05902 GTF2H5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gtf2h5 NCBI NCBI:404672