Ormdl3 - ORM1-like 3 (S. cerevisiae) Gene

Also Known as 2810011N17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66612

Summary

Acts upstream of or within several processes, including negative regulation of B cell apoptotic process; negative regulation of ceramide biosynthetic process; and negative regulation of serine C-palmitoyltransferase activity. Predicted to be located in endoplasmic reticulum. Predicted to be part of SPOTS complex. Is expressed in lung. Orthologous to human ORMDL3 (ORMDL sphingolipid biosynthesis regulator 3). [provided by Alliance of Genome Resources, Apr 2022]

Ormdl3 Products (1)

mRNA Protein Name
NM_025661.4 NP_079937.1 ORM1-like protein 3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of motor behavior IGI
IGI: Inferred from genetic interaction
31880535 MGI
acts upstream of myelination IGI
IGI: Inferred from genetic interaction
31880535 MGI
acts upstream of or within negative regulation of B cell apoptotic process IMP
IMP: Inferred from mutant phenotype
28747345 MGI
acts upstream of or within negative regulation of ceramide biosynthetic process IDA
IDA: Inferred from direct assay
25691431 MGI
acts upstream of or within negative regulation of serine C-palmitoyltransferase activity IMP
IMP: Inferred from mutant phenotype
28275141 MGI
acts upstream of or within positive regulation of autophagy IMP
IMP: Inferred from mutant phenotype
28747345 MGI
acts upstream of regulation of ceramide biosynthetic process IGI
IGI: Inferred from genetic interaction
31880535 MGI
acts upstream of regulation of ceramide biosynthetic process IMP
IMP: Inferred from mutant phenotype
31880535 MGI
acts upstream of regulation of smooth muscle contraction IMP
IMP: Inferred from mutant phenotype
28275141 MGI
acts upstream of regulation of sphingolipid biosynthetic process IGI
IGI: Inferred from genetic interaction
31880535 MGI
acts upstream of regulation of sphingolipid biosynthetic process IMP
IMP: Inferred from mutant phenotype
28275141 MGI
acts upstream of sphingomyelin biosynthetic process IGI
IGI: Inferred from genetic interaction
31880535 MGI
acts upstream of sphingomyelin biosynthetic process IMP
IMP: Inferred from mutant phenotype
31880535 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ORM1-like protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09833 ORMDL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ormdl3 NCBI NCBI:94103