2. Gene
  3. Samd8 - sterile alpha motif domain containing 8 Gene

Samd8 - sterile alpha motif domain containing 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SMSr; 1110053F04Rik; 1700010P07Rik

Gene ID: 67630 | Gene type: protein coding

About Samd8

Summary

Enables ceramide phosphoethanolamine synthase activity. Acts upstream of or within ceramide biosynthetic process and ceramide phosphoethanolamine biosynthetic process. Predicted to be located in cytosol and endoplasmic reticulum. Predicted to be integral component of Golgi membrane; integral component of endoplasmic reticulum membrane; and integral component of plasma membrane. Orthologous to human SAMD8 (sterile alpha motif domain containing 8). [provided by Alliance of Genome Resources, Apr 2022]

Samd8 Products(3)

mRNA Protein Name
NM_001359953.1 NP_001346882.1 sphingomyelin synthase-related protein 1 isoform 3
NM_001359954.1 NP_001346883.1 sphingomyelin synthase-related protein 1 isoform 2
NM_026283.3 NP_080559.1 sphingomyelin synthase-related protein 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables ceramide phosphoethanolamine synthase activity IDA
IDA: Inferred from direct assay
25605874 MGI
enables ceramide phosphoethanolamine synthase activity IMP
IMP: Inferred from mutant phenotype
25605874 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within ceramide biosynthetic process IDA
IDA: Inferred from direct assay
25605874 MGI
acts upstream of or within ceramide biosynthetic process IMP
IMP: Inferred from mutant phenotype
25605874 MGI
acts upstream of or within ceramide phosphoethanolamine biosynthetic process IDA
IDA: Inferred from direct assay
25667419 MGI
acts upstream of or within ceramide phosphoethanolamine biosynthetic process IMP
IMP: Inferred from mutant phenotype
25667419 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sphingomyelin synthase-related protein 1

CPE synthase

GrailEXP prediction

SAM domain-containing protein 8

ceramide phosphoethanolamine synthase

sterile alpha motif domain-containing protein 8

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12430 SAMD8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Samd8 NCBI NCBI:142891