Arhgef12 - Rho guanine nucleotide exchange factor (GEF) 12 Gene

Also Known as Larg; mKIAA0382; 2310014B11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69632

Summary

Predicted to enable G protein-coupled receptor binding activity. Involved in multicellular organism aging and regulation of blood pressure. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and skin. Orthologous to human ARHGEF12 (Rho guanine nucleotide exchange factor 12). [provided by Alliance of Genome Resources, Apr 2022]

Arhgef12 Products (2)

mRNA Protein Name
NM_001359232.1 NP_001346161.1 rho guanine nucleotide exchange factor 12 isoform 2
NM_027144.2 NP_081420.2 rho guanine nucleotide exchange factor 12 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12123608 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of blood pressure IMP
IMP: Inferred from mutant phenotype
26531127 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho guanine nucleotide exchange factor 12

  • leukemia-associated Rho guanine-nucleotide exchange factor

  • leukemia-associated RhoGEF

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00949 ARHGEF12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgef12 NCBI NCBI:23365