Tprkb - Tp53rk binding protein Gene

Also Known as DRWMS1; Cgi-121; mDRWMS1; 0610033G21Rik; 1810034M08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69786

Summary

Predicted to enable protein kinase binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification and telomere maintenance via recombination. Predicted to act upstream of or within tRNA processing. Predicted to be located in cytoplasm. Predicted to be part of EKC/KEOPS complex. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 5. Orthologous to human TPRKB (TP53RK binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Tprkb Products (6)

mRNA Protein Name
NM_001170488.1 NP_001163959.1 EKC/KEOPS complex subunit Tprkb isoform a
NM_001362064.1 NP_001348993.1 EKC/KEOPS complex subunit Tprkb isoform a
NM_001362065.1 NP_001348994.1 EKC/KEOPS complex subunit Tprkb isoform a
NM_001362066.1 NP_001348995.1 EKC/KEOPS complex subunit Tprkb isoform a
NM_001362067.1 NP_001348996.1 EKC/KEOPS complex subunit Tprkb isoform b
NM_176842.3 NP_789812.1 EKC/KEOPS complex subunit Tprkb isoform a
Protein Preferred Names Protein Names

EKC/KEOPS complex subunit Tprkb

  • PRPK-binding protein

  • Prpk (p53-related protein kinase)-binding protein

  • TP53RK-binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14922 TP53RK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-123492 Kentsin Control / Unkown
HY-RS14949 TPRKB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tprkb NCBI NCBI:51002