2. Gene
  3. Sash1 - SAM and SH3 domain containing 1 Gene

Sash1 - SAM and SH3 domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA0790; 1100001C18Rik; 2500002E12Rik; A330076K04Rik

Gene ID: 70097 | Gene type: protein coding

About Sash1

Summary

Predicted to enable several functions, including G-protein alpha-subunit binding activity; mitogen-activated protein kinase kinase kinase binding activity; and protein C-terminus binding activity. Predicted to be involved in positive regulation of JUN kinase activity; positive regulation of NIK/NF-kappaB signaling; and regulation of epithelial cell migration. Predicted to act upstream of or within several processes, including positive regulation of endothelial cell migration; positive regulation of signal transduction; and regulation of protein ubiquitination. Located in membrane. Human ortholog(s) of this gene implicated in dyschromatosis universalis hereditaria. Orthologous to human SASH1 (SAM and SH3 domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Sash1 Products(1)

mRNA Protein Name
NM_175155.4 NP_780364.3 SAM and SH3 domain-containing protein 1
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in membrane IDA
IDA: Inferred from direct assay
23776175 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SAM and SH3 domain-containing protein 1

putative adapter and scaffold protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12452 SASH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sash1 NCBI NCBI:23328