2. Gene
  3. AQP4 - aquaporin 4 Gene

AQP4 - aquaporin 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca mulatta
Gene ID: 703773 | Gene type: protein coding

About AQP4

Summary

This gene encodes a member of the Aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant Aquaporin found in brain and has an important role in brain water homeostasis. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

AQP4 Products(2)

mRNA Protein Name
NM_001257671.2 NP_001244600.1 aquaporin-4 isoform 1
NM_001320538.1 NP_001307467.1 aquaporin-4 isoform 1x
Protein Preferred Names Protein Names

aquaporin-4

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-115460 AER-271 96.90% Phase 1
Pre-clinical Phase
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W008574 TGN-020 99.97% Unkown
HY-W008574A TGN-020 sodium 99.96% Unkown
HY-W176557 TGN-073 99.53% Unkown
HY-P10936A AQP4 (201-220) TFA 99.91% Unkown
HY-N10756 Hyp9 Agonist 99.90% Unkown
HY-N4246 Bacopaside I 99.20% Unkown
HY-157226 ORI-TRN-002 Inhibitor / Unkown
HY-RS00876 AQP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W017091 3-Phenoxy-1,2-propanediol Inhibitor 95.0% Unkown
HY-18805 Nicotinanilide Inhibitor 99.84% Unkown
HY-P10936 AQP4 (201-220) / Unkown
HY-P10937 AQP4 (205-215) / Unkown
HY-P10937A AQP4 (205-215) TFA / Unkown
HY-RS16702 Aqp4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23136 Aqp4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991869 Aquaporumab Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens AQP4 NCBI NCBI:361
Mus musculus AQP4 NCBI NCBI:11829