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RGPD2 - RANBP2 like and GRIP domain containing 2 Gene

Also Known as RGP2; NUP358; RANBP2L2

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 729857

About RGPD2

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:87,755,960-87,989,818 (from NCBI)

This gene has 2 transcripts (splice variants), 21 orthologues and 10 paralogues. Broad expression in testis (RPKM 17.3), placenta (RPKM 6.4) and 23 other tissues.

Summary

Predicted to contribute to GTPase activator activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RGPD2 Products (2)

mRNA	Protein	Name
NM_001078170.3	NP_001071638.2	RANBP2-like and GRIP domain-containing protein 2 isoform 1
NM_001393613.1	NP_001380542.1	RANBP2-like and GRIP domain-containing protein 2 isoform 2

RGPD2 Protein Structure

TPR_1

Ran_BP1

GRIP

0
300
600
900
1200
1500
1756 a.a.

Protein Preferred Names	Protein Names
RANBP2-like and GRIP domain-containing protein 2	Ran binding protein 2-like 2

Related Diseases

Diseases	Alias
Charcot-Marie-Tooth Disease, Axonal, Type 2dd	CMT2DD Charcot-Marie-Tooth Neuropathy, Type 2dd Charcot-Marie-Tooth Disease Type 2dd Atp1a1-Related Autosomal Dominant Charcot-Marie-Tooth Disease Type 2 Atp1a1-Related Cmt2 Autosomal Dominant Charcot-Marie-Tooth Disease Type 2dd Charcot-Marie-Tooth Disease 2dd
Achalasia-Addisonianism-Alacrima Syndrome	Allgrove Syndrome Triple-A Syndrome Achalasia-Addisonianism-Alacrimia Syndrome Alacrima-Achalasia-Adrenal Insufficiency Neurologic Disorder Triple A Syndrome Aaa Syndrome AAAS Glucocorticoid Deficiency With Achalasia Glucocorticoid Deficiency And Achalasia Addisonian-Achalasia Syndrome Hypoadrenalism With Achalasia Alacrima-Achalasia-Addisonianism Aaa Acth-Resistant Adrenal Insufficiency, Achalasia And Alacrima Achalasia Addisonianism Alacrimia Syndrome Achalasia Alacrima Syndrome Addisonian Achalasia Syndrome Achalasia-Addisonian Syndrome Achalasia-Alacrima Syndrome 2a Syndrome 3a Syndrome 4a Syndrome Adrenal Insufficiency-Achalasia-Alacrima Syndrome Double A Syndrome Quaternary A Syndrome Acth-Resistant Adrenal Insufficiency With Achalasia And Alacrima Allgrove'S Syndrome Adrenal Gland Hypofunction Adrenal Cortical Hypofunction

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11898	RGPD1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS11899	RGPD2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	RGPD2	MGD	MGI:894323