PARP8 - poly(ADP-ribose) polymerase family member 8 Gene

Homo sapiens

Also known as ARTD16; pART16

Gene ID: 79668 | Gene type: protein coding

About PARP8

This gene has 22 transcripts (splice variants), 207 orthologues and 2 paralogues. Broad expression in bone marrow (RPKM 11.4), thyroid (RPKM 9.6) and 24 other tissues.

Summary

Enables protein ADP-ribosylase activity. Involved in protein auto-ADP-ribosylation and protein mono-ADP-ribosylation. [provided by Alliance of Genome Resources, Apr 2022]

PARP8 Products(4)

mRNA	Protein	Name
NM_001178055.2	NP_001171526.1	protein mono-ADP-ribosyltransferase PARP8 isoform 1
NM_001178056.2	NP_001171527.1	protein mono-ADP-ribosyltransferase PARP8 isoform 2
NM_001331028.2	NP_001317957.1	protein mono-ADP-ribosyltransferase PARP8 isoform 3
NM_024615.4	NP_078891.2	protein mono-ADP-ribosyltransferase PARP8 isoform 1

Protein Preferred Names

Protein Names

protein mono-ADP-ribosyltransferase PARP8

ADP-ribosyltransferase diphtheria toxin-like 16

Related Diseases

Diseases

Alias

Developmental And Epileptic Encephalopathy 24

DEE24	Epileptic Encephalopathy, Early Infantile, 24
Eiee24	Developmental And Epileptic Encephalopathy, 24
Early Infantile Epileptic Encephalopathy 24	Encephalopathy, Epileptic, Early Infantile, Type 24

Arthrogryposis, Renal Dysfunction, And Cholestasis 1

Arc Syndrome	ARCS1
Arthrogryposis Renal Dysfunction Cholestasis Syndrome	Arthrogryposis-Renal Dysfunction-Cholestasis Syndrome
Arcs	Arthrogryposis, Renal Dysfunction And Cholestasis Syndrome
Arthrogryposis, Renal Dysfunction, And Cholestasis	Arthrogryposis-Renal Dysfunction-Cholestasis
Arthrogryposis - Renal Dysfunction - Cholestasis	Arthrogryposis Multiplex Congenita, Renal Dysfunction, And Cholestasis
Arthrogryposis, Renal Dysfunction And Cholestasis Syndrome 1	Arthrogryposis Renal Dysfunction And Cholestasis 1
Arthrogryposis With Renal Dysfunction And Cholestasis Syndrome	Arthrogryposis, Renal Dysfunction, Cholestasis, Type 1
Kidney Failure	Renal Insufficiency

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10070	PARP8 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PARP8	RGD	RGD:1587384
Felis catus	PARP8	VGNC	VGNC:102281
Mus musculus	PARP8	MGD	MGI:1098713
Canis familiaris	PARP8	VGNC	VGNC:49024
Macaca mulatta	PARP8	VGNC	VGNC:84477

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