ANGPTL6 - angiopoietin like 6 Gene

Also Known as AGF; ARP5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83854

About ANGPTL6

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:10,092,338-10,106,190 (from NCBI)

This gene has 4 transcripts (splice variants), 129 orthologues, 25 paralogues and is associated with 1 phenotype. Ubiquitous expression in liver (RPKM 8.2), spleen (RPKM 5.1) and 25 other tissues.

Summary

Predicted to enable signaling receptor binding activity. Predicted to be involved in angiogenesis and cell differentiation. Located in extracellular exosome. Part of collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

ANGPTL6 Products (4)

mRNA Protein Name
NM_001321411.2 NP_001308340.1 angiopoietin-related protein 6 precursor
NM_001387347.1 NP_001374276.1 angiopoietin-related protein 6 precursor
NM_001387348.1 NP_001374277.1 angiopoietin-related protein 6 precursor
NM_031917.3 NP_114123.2 angiopoietin-related protein 6 precursor

ANGPTL6 Protein Structure

Fibrinogen_C

Fibrinogen_C: Fibrinogen beta and gamma chains, C-terminal globular domain (258 - 467)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 470 a.a.
Protein Preferred Names Protein Names

angiopoietin-related protein 6

  • angiopoietin-like protein 6

Related Diseases

Diseases Alias
Familial Cerebral Saccular Aneurysm

  • Familial Berry Aneurysm

  • Familial Intracranial Saccular Aneurysm
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00695 ANGPTL6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ANGPTL6 VGNC VGNC:59782
Bos taurus ANGPTL6 VGNC VGNC:25894
Macaca mulatta ANGPTL6 VGNC VGNC:108465
Canis familiaris ANGPTL6 VGNC VGNC:37862
Rattus norvegicus ANGPTL6 RGD RGD:1311141
Mus musculus ANGPTL6 MGD MGI:1917976
Others ANGPTL6 NCBI