IPO13 - importin 13 Gene
Also Known as LGL2; IMP13; KAP13; RANBP13
Species: Homo sapiens
About IPO13
This gene has 7 transcripts (splice variants), 212 orthologues, 1 paralogue and is associated with 1 phenotype. Broad expression in testis (RPKM 29.4), brain (RPKM 19.8) and 24 other tissues.
Summary
This gene encodes a member of the importin-beta family of nuclear transport proteins. The encoded protein mediates the import of specific cargo proteins from the cytoplasm to the nucleus and is dependent on the Ras-related nuclear protein-GTPase system. The encoded protein is also involved in nuclear export of the eukaryotic translation initiation factor 1A.[provided by RefSeq, Mar 2009]
IPO13 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_014652.4 | NP_055467.3 | importin-13 |
IPO13 Protein Structure
IBN_N: Importin-beta N-terminal domain (45 - 109)
Xpo1: Exportin 1-like protein (117 - 262)
- 0
- 200
- 400
- 600
- 800
- 963 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
importin-13 |
|
IPO13 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
IPO13 | O94829 | PBX4 | Homo sapiens | Q9BYU1 | 25416956 | |
|
Intra
|
IPO13 | O94829 | PBX4 | Homo sapiens | Q9BYU1 | 29892012 | |
|
Intra
|
IPO13 | O94829 | PBX4 | Homo sapiens | Q9BYU1 | 31515488 | |
|
Intra
|
IPO13 | O94829 | PBX4 | Homo sapiens | Q9BYU1 | 32296183 | |
|
Intra
|
IPO13 | O94829 | PBX4 | Homo sapiens | Q9BYU1 | 25416956 | |
|
Intra
|
IPO13 | O94829 | EIF1AX | Homo sapiens | P47813 | 23435562 | |
|
Intra
|
IPO13 | O94829 | EIF1AX | Homo sapiens | P47813 | 23435562 | |
|
Intra
|
IPO13 | O94829 | EIF1AX | Homo sapiens | P47813 | 21139563 | |
|
Intra
|
IPO13 | O94829 | PAX3 | Homo sapiens | P23760-8 | 32296183 | |
|
Intra
|
IPO13 | O94829 | HMBOX1 | Homo sapiens | Q6NT76 | 32296183 | |
|
Intra
|
IPO13 | O94829 | RAN | Homo sapiens | P62826 | 21139563 | |
|
Intra
|
IPO13 | O94829 | RAN | Homo sapiens | P62826 | 21139563 | |
|
Intra
|
IPO13 | O94829 | RAN | Homo sapiens | P62826 | 23435562 | |
|
Intra
|
IPO13 | O94829 | MAGOH | Homo sapiens | P61326 | 23435562 | |
|
Intra
|
IPO13 | O94829 | MAGOH | Homo sapiens | P61326 | 23435562 | |
|
Intra
|
IPO13 | O94829 | MAGOH | Homo sapiens | P61326 | 21139563 | |
|
Intra
|
IPO13 | O94829 | PSMA1 | Homo sapiens | P25786 | 32296183 | |
|
Intra
|
IPO13 | O94829 | PITX1 | Homo sapiens | P78337 | 32296183 | |
|
Intra
|
IPO13 | O94829 | UBE2I | Homo sapiens | P63279 | 23435562 | |
|
Intra
|
IPO13 | O94829 | UBE2I | Homo sapiens | P63279 | 23435562 | |
|
Intra
|
IPO13 | O94829 | UBE2I | Homo sapiens | P63279 | 21139563 | |
|
Intra
|
IPO13 | O94829 | UBE2I | Homo sapiens | P63279 | 21139563 |
IPO13 Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P89596 | karyopherin 13 Antibody (YA8940) | WB, ICC/IF, IF-Tissue, IP, ELISA | human, mouse, rat |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Partington Syndrome |
|
|
| Corpus Callosum, Agenesis Of, With Abnormal Genitalia |
|
|
| Myiasis |
|
|
| Lissencephaly, X-Linked, 2 |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | IPO13 | MGD | MGI:2385205 |
| Rattus norvegicus | IPO13 | RGD | RGD:620071 |
| Canis familiaris | IPO13 | VGNC | VGNC:42064 |
| Bos taurus | IPO13 | VGNC | VGNC:30241 |
| Macaca mulatta | IPO13 | VGNC | VGNC:73609 |
| Felis catus | IPO13 | VGNC | VGNC:62954 |
| Others | IPO13 | NCBI |