1. Metabolic Enzyme/Protease
  2. Glutaminase
  3. IPN-60090

IPN-60090 

Cat. No.: HY-103671
Handling Instructions

IPN-60090 is an orally bioavailable and selective inhibitor of GLS1 (the kidney-type glutaminase), an important enzyme for metabolic energy production. IPN-60090 can be used in the research of GLS1-mediated diseases.

For research use only. We do not sell to patients.

IPN-60090 Chemical Structure

IPN-60090 Chemical Structure

CAS No. : 1853164-83-6

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Description

IPN-60090 is an orally bioavailable and selective inhibitor of GLS1 (the kidney-type glutaminase), an important enzyme for metabolic energy production. IPN-60090 can be used in the research of GLS1-mediated diseases[1][2].

IC50 & Target

GLS1[1]

In Vitro

IPN-60090 (Example 1) has an IC50 against GLS1 and an EC50 against A549 cell proliferation of <100 nM[2].

Molecular Weight

532.52

Formula

C₂₄H₂₇F₃N₈O₃

CAS No.

1853164-83-6

SMILES

O=C(NC1=NN=C(CC[[email protected]@H](F)CN2N=NC(C(NC)=O)=C2)C=C1)CC3=NC(C)=CC(OC4CC(F)(F)C4)=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

IPN-60090IPN60090IPN 60090Glutaminasekidney-typeglutaminaseGLS1cancerimmunologicalneurologicaldisordersInhibitorinhibitorinhibit

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