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Cat. No.: HY-183001

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ATX-012

ATX-012 is an ionizable cationic lipid. ATX-012 can be used to prepare lipid formulations that encapsulate CFTR mRNA. ATX-012 is applicable to research related to cystic fibrosis.

For research use only. We do not sell to patients.

CAS No.: 1777792-44-5
Formula: C₄₂H₇₈N₂O₅S
Molecular Weight:723.14

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

ATX-012 Chemical Structure

CAS No.: 1777792-44-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

ATX-012 is an ionizable cationic lipid. ATX-012 can be used to prepare lipid formulations that encapsulate CFTR mRNA. ATX-012 is applicable to research related to cystic fibrosis^[1].

Chemical Information

CAS No. 1777792-44-5
Molecular Weight 723.14
Formula C₄₂H₇₈N₂O₅S
SMILES

CCN(CCCSC(N(CCCCCCCC(OC/C=C\CCCCCC)=O)CCCCCCCC(OC/C=C\CCCCCC)=O)=O)CC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Carlos G, et al. Lipid formulations containing nucleic acids and methods of treatment for cystic fibrosis. US20230159449A1. United States. 2022-11-03.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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