Normethyl-ZCAN262
Normethyl-ZCAN262 (Normethyl-262) is a blood-brain barrier-permeable selective GluR2/AMPAR receptor modulator. Normethyl-ZCAN262 inhibits AMPA-mediated neurotoxicity, the formation of the GAPDH-GluR2 complex, and GluR2/AMPAR neurotoxicity. Normethyl-ZCAN262 enables in vivo imaging of brain AMPA receptors and is used in research related to multiple sclerosis, amyotrophic lateral sclerosis, neuroinflammation, stroke, epilepsy, Parkinson's disease, Alzheimer's disease, dementia, and Huntington's disease.
For research use only. We do not sell to patients.
- CAS No.: 3080492-21-0
- Formula: C18H16F2N6O
- Molecular Weight:370.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All iGluR Isoforms
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Biological Activity
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AMPA Receptor |
Chemical Information
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CAS No. 3080492-21-0
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Molecular Weight 370.36
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Formula C18H16F2N6O
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SMILES
O=C(C1=NC(N2CC3=NN(CC4=CC=C(C=C4F)F)C=C3C2)=NC=C1)NC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)