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Cat. No.: HY-N18290

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12-Ethoxynimbolinin E

12-Ethoxynimbolinin E is a nimbolinin-type limonoid found in the fruits of Melia toosendan. 12-Ethoxynimbolinin E induces cytotoxic activity against cancer cells. 12-Ethoxynimbolinin E can be used for the research of cancer, such as myeloid leukemia, and lung cancer.

For research use only. We do not sell to patients.

CAS No.: 1941147-56-3
Formula: C₃₅H₄₄O₈
Molecular Weight:592.72

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

12-Ethoxynimbolinin E Chemical Structure

CAS No.: 1941147-56-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

12-Ethoxynimbolinin E (Compound 1) inhibits viability of HL-60, A-549, MCF-7, and SW480 human tumor cell lines with IC₅₀ values of 21.5, 26.4, 25.2, and 31.8 μM, respectively, and does not inhibit viability of SMMC-7721 cells at concentrations up to 40 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1941147-56-3
Molecular Weight 592.72
Formula C₃₅H₄₄O₈
SMILES

C[C@]12[C@@]3([H])[C@](OC[C@@]3([C@@H](C[C@@H]2OC(C4=CC=CC=C4)=O)O)C)([H])[C@H]([C@@]5([C@]1([H])C[C@@H](O[C@]6([H])C5=C([C@H](C7=COC=C7)C6)C)OCC)C)O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang Q, et al. Two new nimbolinin‐type limonoids from the fruits of Melia toosendan[J]. Helvetica Chimica Acta, 2016, 99(6): 462-465.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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