Isolobetyol
Isolobetyol is a polyacetylene found in whole plants of Lobelia chinensis. Isolobetyol shows cytotoxic effects against cancer cells. Isolobetyol can be used for the research of cancer, such as human lung cancer and biphasic mesothelioma.
For research use only. We do not sell to patients.
- CAS No.: 1621230-88-3
- Formula: C14H18O3
- Molecular Weight:234.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Isolobetyol (Compound 8) (48 h) exhibits moderate cytotoxic activity against MSTO-211H biphasic mesothelioma cells and NCI-H292 human lung mucoepidermoid carcinoma cells, with IC50 values of 12.36 μM and 9.31 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:NCI-H292 human lung mucoepidermoid carcinoma cells, MSTO-211H biphasic mesothelioma cells
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Concentration:IC50 9.31 μM (NCI-H292); IC50 12.36 μM (MSTO-211H)
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Incubation Time:48 h
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Result:Exhibited moderate cytotoxic activity with an IC50 of 12.36 μM against MSTO-211H cells.
Showed moderate cytotoxic activity with an IC50 of 9.31 μM against NCI-H292 cells.
Chemical Information
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CAS No. 1621230-88-3
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Molecular Weight 234.29
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Formula C14H18O3
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SMILES
OCCC/C=C/C(O)C(O)C#CC#C/C=C\C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)