TMEM175 agonist 1
TMEM175 agonist 1 is a TMEM175 agonist, with a human EC50 of 0.378 μM in FLIPR assays and a human EC50 of 0.886 μM in EP analyses. TMEM175 agonist 1 can be used in the research of Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases.
For research use only. We do not sell to patients.
- CAS No.: 3129653-69-3
- Formula: C27H26F3N5O5S
- Molecular Weight:589.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
TMEM175 agonist 1 (Compound 232) activates human TMEM175 in FLIPR assays, with an EC50 of 0.378 μM[1].
TMEM175 agonist 1 activates human TMEM175 in EP assays, with an EC50 value of 0.886 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3129653-69-3
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Molecular Weight 589.59
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Formula C27H26F3N5O5S
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SMILES
CO[C@@H](C1=NC2=C(C(N1NS(=O)(C3=CC=C(C=C3)N[C@@H]4C[C@@H](C4)OC(F)F)=O)=O)C=CN=C2C)C5=CC=C(C=C5)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TMEM175 agonist 1 Related Classifications
HY-186253 Related Classifications
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