ANGPTL
Angiopoietin-like protein
Angiopoietin-like proteins (ANGPTLs) are identified as proteins structurally similar to angiopoietins, and the ANGPTL family now consists of eight members. ANGPTLs are secretary proteins, and some ANGPTLs are not only angiogenic factors but also proteins with multiple functions such as glucose metabolism, lipid metabolism, redox regulation and chronic inflammation.
ANGPTL アイソフォーム特異的製品
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ANGPTL 関連製品 (19)
関連製品 (19)
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ANGPTL Isoform Comparison
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Evinacumab
0 Images別名: REGN1500Evinacumab (REGN1500) is a human anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia.
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Vupanorsen sodium
0 Images別名: IONIS ANGPT-L3Rx sodium; ISIS 703802 sodiumVupanorsen (sodium) is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen (sodium) lowers triglycerides and atherogenic lipoproteins.
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Anti-ANGPTL4 Antibody
0 Images製品番号: HY-P990335Anti-ANGPTL4 Antibody is a CHO expressed human antibody targeting ANGPTL4. Anti-ANGPTL4 Antibody has a huIgG1-type heavy chain and a huλ-type light chain with a predicted molecular weight (MW) of 150 kDa. An isotype control for Anti-ANGPTL4 Antibody can be found in Human IgG1 kappa, Isotype Control (HY-P99001).
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Zodasiran
0 Images製品番号: HY-177671CAS 番号: 2232918-66-8別名: ARO-ANG3Zodasiran is a siRNA targeted to ANGPTL3 in the liver.
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Pegevongitide
0 Images別名: AV-001Pegevongitide is an agonist of the angiopoietin-1 receptor.
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Corveldebart
0 ImagesCorveldebart is a monoclonal antibody of immunoglobulin G1-kappa that targets ANGPTL4. Corveldebart can be used as an immunomodulator.
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Lexosiran
0 Images製品番号: HY-185318CAS 番号: 3078403-66-1Lexosiran is a siRNA that inhibits ANGPTL3 (angiopoietin-related protein 3) synthesis, and can be use for the study of antihyperlipidaemic.
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Zodasiran sodium scrambled negative control
0 Images製品番号: HY-177671BZodasiran sodium scrambled negative control is the sequence scrambled negative control of Zodasiran sodium.
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JTE-907
0 ImagesJTE-907 is a selective and orally active cannabinoid CB2 receptor inverse agonist and exerts anti-inflammatory effects. JTE-907 upregulates IL-6, MCP-1, IL-1β, VEGF, ANGPTL4, and TRPV1 in mature adipocytes. JTE-907 downregulates CB1, MCP-1, and IL-1β in preadipocytes. JTE-907 inhibits ear swelling in mice. JTE-907 reverses the protective effects of CB2 agonists and Anandamide (HY-10863) against cytokine-evoked colonic mucosal damage. JTE-907 can be used for the research of allergic dermatitis, obesity, and colitis.
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DC371739
0 Images製品番号: HY-163794CAS 番号: 2135765-21-6
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Vupanorsen
0 Images製品番号: HY-153497CAS 番号: 2097587-62-5別名: IONIS ANGPT-L3Rx; ISIS 703802Vupanorsen is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen lowers triglycerides and atherogenic lipoproteins.
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Zodasiran sodium
0 Images製品番号: HY-177671ACAS 番号: 2232918-74-8別名: ARO-ANG3 sodiumZodasiran sodium is a siRNA targeted to ANGPTL3 in the liver.
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Solbinsiran sodium
0 Images製品番号: HY-177666ACAS 番号: 2707429-60-3別名: LY3561774 sodiumSolbinsiran sodium is a siRNA targeted to hepatic ANGPTL3.
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Solbinsiran sodium scrambled negative control
0 Images製品番号: HY-177666BSolbinsiran sodium scrambled negative control is the sequence scrambled negative control of Solbinsiran sodium.
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Lexosiran sodium
0 Images製品番号: HY-185318ALexosiran sodium is a siRNA that inhibits ANGPTL3 angiopoietin-related protein 3 synthesis, and can be use for the study of antihyperlipidaemic.
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Solbinsiran
0 Images製品番号: HY-177666CAS 番号: 2718150-11-7別名: LY3561774Solbinsiran is a siRNA targeted to hepatic ANGPTL3.
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Cartilostatin 1
0 Images製品番号: HY-P4000CAS 番号: 929555-05-5Cartilostatin 1 is an anti-angiogenic peptide. Cartilostatin 1 can be used for the research of anti-angiogenic.
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Vupanorsen sodium scrambled negative control
0 Images製品番号: HY-153497CVupanorsen sodium scrambled negative control is the sequence scrambled negative control of Vupanorsen sodium.
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Anti-ANGPTL8 Antibody
0 Images製品番号: HY-P990336Anti-ANGPTL8 Antibody is a CHO expressed human antibody targeting ANGPTL8. Anti-ANGPTL8 Antibody has a huIgG1-type heavy chain and a huκ-type light chain with a predicted molecular weight (MW) of 150 kDa. An isotype control for Anti-ANGPTL8 Antibody can be found in Human IgG2 kappa, Isotype Control (HY-P99002).
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