AMPK activator 14
AMPK activator 14 (compound 32) is an orally active AMPK activator. AMPK activator 14 decreases fasted glucose and insulin levels in a db/db mouse model of Type II diabetes.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1356632-18-2
- 分子式: C33H34FN5O4
- 分子量:583.65
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
AMPK アイソフォーム固有の製品をすべて表示
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>20 μM
Compound: 32
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Cytotoxicity against human A549 cells assessed as reduction in cell growth
Cytotoxicity against human A549 cells assessed as reduction in cell growth
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[PMID: 38079537] |
| HepG2 | IC50 |
1.171 μM
Compound: 32
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Inhibition of mitochondrial function in human HepG2 cells assessed as reduction in ATP production
Inhibition of mitochondrial function in human HepG2 cells assessed as reduction in ATP production
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[PMID: 38079537] |
| NCI-H1299 | IC50 |
>20 μM
Compound: 32
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Cytotoxicity against human NCI-H1299 cells assessed as reduction in cell growth
Cytotoxicity against human NCI-H1299 cells assessed as reduction in cell growth
|
[PMID: 38079537] |
化学情報
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CAS 番号 1356632-18-2
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分子量 583.65
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分子式 C33H34FN5O4
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SMILES
COC1=CC=C(C=C1)C(C2CCN(CC2)C(C3=NC=C(C=C3)C(N[C@H]4CCN(CC5=CC=C(C=C5)C#N)C[C@@H]4F)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
AMPK activator 14 関連分類
HY-162042 関連分類
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