Bromo-PEG8-Boc
Based on 1 Customer Validation
Bromo-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 1623792-00-6
- 分子式: C23H45BrO10
- 分子量:561.50
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1623792-00-6
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性状 Liquid (Density: 1.18 g/cm3)
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分子量 561.50
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分子式 C23H45BrO10
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCBr
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 87.5 mg/mL (155.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7809 mL | 8.9047 mL | 17.8094 mL | 44.5236 mL |
| 5 mM | 0.3562 mL | 1.7809 mL | 3.5619 mL | 8.9047 mL | |
| 10 mM | 0.1781 mL | 0.8905 mL | 1.7809 mL | 4.4524 mL | |
| 15 mM | 0.1187 mL | 0.5936 mL | 1.1873 mL | 2.9682 mL | |
| 20 mM | 0.0890 mL | 0.4452 mL | 0.8905 mL | 2.2262 mL | |
| 25 mM | 0.0712 mL | 0.3562 mL | 0.7124 mL | 1.7809 mL | |
| 30 mM | 0.0594 mL | 0.2968 mL | 0.5936 mL | 1.4841 mL | |
| 40 mM | 0.0445 mL | 0.2226 mL | 0.4452 mL | 1.1131 mL | |
| 50 mM | 0.0356 mL | 0.1781 mL | 0.3562 mL | 0.8905 mL | |
| 60 mM | 0.0297 mL | 0.1484 mL | 0.2968 mL | 0.7421 mL | |
| 80 mM | 0.0223 mL | 0.1113 mL | 0.2226 mL | 0.5565 mL | |
| 100 mM | 0.0178 mL | 0.0890 mL | 0.1781 mL | 0.4452 mL |