Bromo-PEG2-C2-Boc
Based on 1 Customer Validation
Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 1381861-91-1
- Formula: C11H21BrO4
- Molecular Weight:297.19
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1381861-91-1
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Appearance Liquid (Density: 1.240±0.06 g/cm3)
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Molecular Weight 297.19
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Formula C11H21BrO4
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)CCOCCOCCBr
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (336.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3649 mL | 16.8243 mL | 33.6485 mL | 84.1213 mL |
| 5 mM | 0.6730 mL | 3.3649 mL | 6.7297 mL | 16.8243 mL | |
| 10 mM | 0.3365 mL | 1.6824 mL | 3.3649 mL | 8.4121 mL | |
| 15 mM | 0.2243 mL | 1.1216 mL | 2.2432 mL | 5.6081 mL | |
| 20 mM | 0.1682 mL | 0.8412 mL | 1.6824 mL | 4.2061 mL | |
| 25 mM | 0.1346 mL | 0.6730 mL | 1.3459 mL | 3.3649 mL | |
| 30 mM | 0.1122 mL | 0.5608 mL | 1.1216 mL | 2.8040 mL | |
| 40 mM | 0.0841 mL | 0.4206 mL | 0.8412 mL | 2.1030 mL | |
| 50 mM | 0.0673 mL | 0.3365 mL | 0.6730 mL | 1.6824 mL | |
| 60 mM | 0.0561 mL | 0.2804 mL | 0.5608 mL | 1.4020 mL | |
| 80 mM | 0.0421 mL | 0.2103 mL | 0.4206 mL | 1.0515 mL | |
| 100 mM | 0.0336 mL | 0.1682 mL | 0.3365 mL | 0.8412 mL |