Br-PEG3-C2-Boc
Based on 1 Customer Validation
Br-PEG3-C2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 782475-37-0
- Formula: C13H25BrO5
- Molecular Weight:341.24
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 782475-37-0
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Appearance Liquid (Density: 1.223±0.06 g/cm3)
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Molecular Weight 341.24
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Formula C13H25BrO5
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)CCOCCOCCOCCBr
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (293.05 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9305 mL | 14.6524 mL | 29.3049 mL | 73.2622 mL |
| 5 mM | 0.5861 mL | 2.9305 mL | 5.8610 mL | 14.6524 mL | |
| 10 mM | 0.2930 mL | 1.4652 mL | 2.9305 mL | 7.3262 mL | |
| 15 mM | 0.1954 mL | 0.9768 mL | 1.9537 mL | 4.8841 mL | |
| 20 mM | 0.1465 mL | 0.7326 mL | 1.4652 mL | 3.6631 mL | |
| 25 mM | 0.1172 mL | 0.5861 mL | 1.1722 mL | 2.9305 mL | |
| 30 mM | 0.0977 mL | 0.4884 mL | 0.9768 mL | 2.4421 mL | |
| 40 mM | 0.0733 mL | 0.3663 mL | 0.7326 mL | 1.8316 mL | |
| 50 mM | 0.0586 mL | 0.2930 mL | 0.5861 mL | 1.4652 mL | |
| 60 mM | 0.0488 mL | 0.2442 mL | 0.4884 mL | 1.2210 mL | |
| 80 mM | 0.0366 mL | 0.1832 mL | 0.3663 mL | 0.9158 mL | |
| 100 mM | 0.0293 mL | 0.1465 mL | 0.2930 mL | 0.7326 mL |
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