Bromo-PEG1-C2-Boc
Based on 1 Customer Validation
Bromo-PEG1-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.54%
- CAS No.: 1393330-36-3
- Formula: C9H17BrO3
- Molecular Weight:253.13
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1393330-36-3
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Appearance Liquid (Density: 1.264±0.06 g/cm3)
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Molecular Weight 253.13
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Formula C9H17BrO3
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)CCOCCBr
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : ≥ 100 mg/mL (395.05 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.9505 mL | 19.7527 mL | 39.5054 mL | 98.7635 mL |
| 5 mM | 0.7901 mL | 3.9505 mL | 7.9011 mL | 19.7527 mL | |
| 10 mM | 0.3951 mL | 1.9753 mL | 3.9505 mL | 9.8763 mL | |
| 15 mM | 0.2634 mL | 1.3168 mL | 2.6337 mL | 6.5842 mL | |
| 20 mM | 0.1975 mL | 0.9876 mL | 1.9753 mL | 4.9382 mL | |
| 25 mM | 0.1580 mL | 0.7901 mL | 1.5802 mL | 3.9505 mL | |
| 30 mM | 0.1317 mL | 0.6584 mL | 1.3168 mL | 3.2921 mL | |
| 40 mM | 0.0988 mL | 0.4938 mL | 0.9876 mL | 2.4691 mL | |
| 50 mM | 0.0790 mL | 0.3951 mL | 0.7901 mL | 1.9753 mL | |
| 60 mM | 0.0658 mL | 0.3292 mL | 0.6584 mL | 1.6461 mL | |
| 80 mM | 0.0494 mL | 0.2469 mL | 0.4938 mL | 1.2345 mL | |
| 100 mM | 0.0395 mL | 0.1975 mL | 0.3951 mL | 0.9876 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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