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製品番号: HY-N20699

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Geministatin C

Geministatin C is a depside analog derived from Geministatin A (HY-N20700) that exhibits mammalian cytotoxicity against cancer cells and fibroblasts. Geministatin C shows no significant antibacterial activity against Gram-positive bacteria and no antifungal activity against yeast.

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CAS 番号: 3131756-59-4
分子式: C₃₁H₄₈O₉
分子量:564.71

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Geministatin C 構造式

CAS 番号: 3131756-59-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Geministatin C exhibits no significant antibacterial activity against Bacillus subtilis, Staphylococcus aureus, or methicillin-resistant S. aureus, with MIC values > 100 μg/mL for all three bacterial strains^[1].
Geministatin C exhibits no significant antifungal activity against Saccharomyces cerevisiae, with an MIC value > 200 μg/mL^[1].
Geministatin C exhibits cytotoxicity against mouse myeloma NS-1 cells with an IC₅₀ of 17 μM and against neonatal foreskin fibroblast (NFF) cells with an IC₅₀ of 19 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 3131756-59-4
分子量 564.71
分子式 C₃₁H₄₈O₉
SMILES

CCCCC/C=C\C/C=C\CCCCCCCC(C=C1O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O)O)=C(C(O)=C1)C(OC)=O
Structure Classification
- Phenols
- Monophenols
Initial Source
- Microorganisms
Austroacremonium gemini
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Crombie A, et al. Geministatins: new depside antibiotics from the fungus Austroacremonium gemini. The Journal of antibiotics. 2024 Oct;77(10):639-646. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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