Hydroxydihydrobovolide
Hydroxydihydrobovolide is a α-β-unsaturatedγ-lactone found in Portulaca oleracea L.. Hydroxydihydrobovolide shows cytotoxicity against cancer cells and shows anti-HIV-1 activity (IC50 = 122.7 μM). Hydroxydihydrobovolide can be used for the researches of neuroblastoma and HIV-1 infection.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1403940-81-7
- 分子式: C11H18O3
- 分子量:198.26
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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HIV-1 122.7 μM (IC50) |
Hydroxydihydrobovolide (Compound HDB) (0.01-50 μM; 48 h) has significant cytotoxicity on SH-SY5Y cells at 50 μM[1].
Hydroxydihydrobovolide inhibits HIV-1 replication with an IC50 of 122.7 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SH-SY5Y human neuroblastoma cells
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Concentration:0.01, 0.1, 1, 10, 50 μM
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Incubation Time:48 h
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Result:Did not cause a statistically significant decrease in SH-SY5Y cell viability at 0.01-10 μM.
Significantly inhibited SH-SY5Y cell growth at 50 μM.
化学情報
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CAS 番号 1403940-81-7
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分子量 198.26
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分子式 C11H18O3
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SMILES
CCCCC[C@]1(C(C)=C(C(O1)=O)C)O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)