LDH-IN-4
LDH-IN-4 is a LDHA and LDHB inhibitor, as well as a ligand for target protein for PROTACs. LDH-IN-4 can be used to synthesize proteolysis-targeting chimeras (PROTAC), such as MS6105 (HY-152261). LDH-IN-4 is applicable to pancreatic cancer-related research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C30H31N5O4S2
- 分子量:589.73
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
LDHA |
LDHB |
LDH-IN-4 acts as a target protein ligand for MS6105 (HY-152261), a lactate dehydrogenase (LDH) proteolysis-targeting chimera (PROTAC) that effectively degrades LDHA and LDHB in a time- and ubiquitin-proteasome system-dependent manner, with anticancer activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
分子量 589.73
-
分子式 C30H31N5O4S2
-
SMILES
NCCCCC#CC1=CC=CC(C2=NN(C(CC3CC3)=C2CC4=CC=C(C=C4)S(N)(=O)=O)C5=NC(C(O)=O)=CS5)=C1
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)