MDTF free acid
MDTF free acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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- CAS 番号: 2102021-49-6
- 分子式: C16H11F4NO9S
- 分子量:469.32
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
MDTF free acid (50?μM) increases hydrophilic character by substitution of a cyclohexyl ring and a MD-based FRET probe incubates in human plasma has a considerably higher self-stabilization rate compared to the MCC-based probe[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2102021-49-6
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分子量 469.32
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分子式 C16H11F4NO9S
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SMILES
O=C([C@H]1CO[C@H](OC1)CN2C(C=CC2=O)=O)OC3=C(C(F)=C(C(F)=C3F)S(=O)(O)=O)F
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)